Migrasomes: Biogenesis, Physiological Roles, and Therapeutic Potentials

Overview

Journal J Cell Biol

Specialty Cell Biology

Date 2024 Oct 14

PMID 39400310

Authors

Haifeng Jiao

Li Yu

Affiliations

Soon will be listed here.

Abstract

Migrasomes, vesicular structures discovered in migrating cells, arise from the junctions or tips of retraction fibers, and gradually grow to microscale vesicles. Migrasomes have garnered attention for their role in intercellular communication and potential therapeutic implications. This review presents an overview of recent advances in migrasome biology, covering the mechanisms of migrasome biogenesis, essential physiological roles, and their association with various diseases, alongside potential therapeutic applications. Furthermore, we share our perspectives on potential future directions in the study of migrasomes and highlight the challenges that remain in this developing area of research.

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