Functional Movement Disorders and Deep Brain Stimulation: A Review

Overview

Journal Neurol Clin Pract

Date 2024 Oct 14

PMID 39399566

Authors

Alexandra Boogers

Alfonso Fasano

Affiliations

Soon will be listed here.

Abstract

Purpose Of The Review: The aim of this narrative review was to explore the interplay between functional movement disorders (FMDs) and deep brain stimulation (DBS).

Recent Findings: Patients with unrecognized FMD who are referred for DBS usually present with functional dystonia. By contrast, patients who present with FMD after DBS are mostly presenting with functional tremor, in keeping with non-DBS FMD cohorts. Comorbid presentation of FMD in established DBS indications makes the decision to opt for surgery challenging. Many contributing factors can play a role in the development of FMD, including the trauma caused by awake neurosurgery and/or extensive DBS programming.

Summary: FMDs in the context of DBS are often overlooked and should be diagnosed promptly because they determine surgical outcome. The approach to DBS candidates with comorbid FMD and the risk factors of FMD after DBS should be further explored.

Citing Articles

Psychiatric Disorders and Cognitive Fluctuations in Parkinson's Disease: Changing Approaches in the First Decades of the 21st Century.

Onofrj M, De Rosa M, Russo M, Ajdinaj P, Calisi D, Thomas A Brain Sci. 2025; 14(12.

PMID: 39766432 PMC: 11727288. DOI: 10.3390/brainsci14121233.

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