» Articles » PMID: 39382272

Impact of High-speed Nanodroplets on Various Pathogenic Bacterial Cell Walls

Overview
Journal J Bacteriol
Specialty Microbiology
Date 2024 Oct 9
PMID 39382272
Authors
Affiliations
Soon will be listed here.
Abstract

Importance: Although existing disinfection techniques demonstrate bactericidal effects through chemical reactions, concerns regarding human toxicity and environmental contamination have been raised. To the best of our knowledge, this study is the first in the world to reveal that the use of this technology, with nanodroplets of less than 100 nm, can destroy and sterilize bacterial cells by colliding with biofilm-forming bacteria at 75 MPa. Furthermore, because this technology uses only water, it can solve the problems of human toxicity and environmental contamination caused by existing disinfection techniques. Because of its minimal water usage, it can be employed for sanitation worldwide without being limited to specific regions. Our report proposes an unprecedented physical disinfection approach that utilizes a high-speed nanodroplet generation technology.

References
1.
De Geyter D, Blommaert L, Verbraeken N, Sevenois M, Huyghens L, Martini H . The sink as a potential source of transmission of carbapenemase-producing in the intensive care unit. Antimicrob Resist Infect Control. 2017; 6:24. PMC: 5314675. DOI: 10.1186/s13756-017-0182-3. View

2.
Schweitzer M, Moyer A, Zheng W . Testing the Hypothesis of Biofilm as a Source for Soft Tissue and Cell-Like Structures Preserved in Dinosaur Bone. PLoS One. 2016; 11(2):e0150238. PMC: 4771714. DOI: 10.1371/journal.pone.0150238. View

3.
Rosenberg B, Kemeny G, Switzer R, Hamilton T . Quantitative evidence for protein denaturation as the cause of thermal death. Nature. 1971; 232(5311):471-3. DOI: 10.1038/232471a0. View

4.
Yamano N, Kunisada M, Kaidzu S, Sugihara K, Nishiaki-Sawada A, Ohashi H . Long-term Effects of 222-nm ultraviolet radiation C Sterilizing Lamps on Mice Susceptible to Ultraviolet Radiation. Photochem Photobiol. 2020; 96(4):853-862. PMC: 7497027. DOI: 10.1111/php.13269. View

5.
Clements-Decker T, Rautenbach M, Khan S, Khan W . Metabolomics and Genomics Approach for the Discovery of Serrawettin W2 Lipopeptides from NP2. J Nat Prod. 2022; 85(5):1256-1266. DOI: 10.1021/acs.jnatprod.1c01186. View