Recurrent Pericarditis and Paradigm Shift in Cardiovascular Imaging and Targeted Therapeutics

Overview

Journal JACC Adv

Specialty Cardiology & Vascular Diseases

Date 2024 Oct 7

PMID 39372451

Authors

Rehan Karmali

Tahir S Kafil

Aqieda Bayat

Bianca Honnekeri

Osamah Badwan

Felix Berglund

Paul Cremer

Allan L Klein

Affiliations

Soon will be listed here.

Abstract

Recurrent pericarditis poses a significant challenge to patients and clinicians given its high morbidity and health care burden. Since the last iteration of European Society of Cardiology Guidelines in 2015, further insights have been gained into the pathophysiology, multimodality imaging assessment, and treatment of this condition. The purpose of this review is to discuss each of these aspects and highlight the role of imaging-guided therapy and interleukin-1 inhibitors in autoinflammatory phenotypes that together have transformed the care of these patients. Although future investigations are needed to optimize diagnostic surveillance and timing of therapy, recent evidence points at an encouraging paradigm shift in the treatment of recurrent pericarditis.

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