» Articles » PMID: 39371730

Monkeypox: A Growing Concern for Pulmonary Health

Overview
Journal Cureus
Date 2024 Oct 7
PMID 39371730
Authors
Affiliations
Soon will be listed here.
Abstract

The re-emergence of monkeypox as a significant global health concern has highlighted the need to reassess its clinical presentation, particularly its impact on pulmonary health. Traditionally associated with dermatological symptoms, recent outbreaks in non-endemic regions have underscored the virus's potential for widespread transmission and respiratory complications. Emerging evidence indicates that monkeypox infection can lead to respiratory symptoms such as cough, sore throat, and, in severe cases, pneumonia and acute respiratory distress syndrome (ARDS). The virus's capacity for respiratory transmission, coupled with the potential for coinfection with other respiratory pathogens, poses significant challenges for clinical management. Understanding the pathophysiology of monkeypox's impact on the lungs, which may involve direct viral invasion and immune-mediated damage, is critical for developing effective public health strategies. As monkeypox continues to spread, recognizing and addressing its respiratory complications will be essential in mitigating severe outcomes, particularly in vulnerable populations with pre-existing pulmonary conditions.

References
1.
Reynolds M, Yorita K, Kuehnert M, Davidson W, Huhn G, Holman R . Clinical manifestations of human monkeypox influenced by route of infection. J Infect Dis. 2006; 194(6):773-80. DOI: 10.1086/505880. View

2.
Hakim M, Widyaningsih S . The recent re-emergence of human monkeypox: Would it become endemic beyond Africa?. J Infect Public Health. 2023; 16(3):332-340. PMC: 9846899. DOI: 10.1016/j.jiph.2023.01.011. View

3.
Sreenath K, Batra P, Vinayaraj E, Bhatia R, Saikiran K, Singh V . Coinfections with Other Respiratory Pathogens among Patients with COVID-19. Microbiol Spectr. 2021; 9(1):e0016321. PMC: 8552727. DOI: 10.1128/Spectrum.00163-21. View

4.
Mitja O, Ogoina D, Titanji B, Galvan C, Muyembe J, Marks M . Monkeypox. Lancet. 2022; 401(10370):60-74. PMC: 9671644. DOI: 10.1016/S0140-6736(22)02075-X. View

5.
Adler H, Gould S, Hine P, Snell L, Wong W, Houlihan C . Clinical features and management of human monkeypox: a retrospective observational study in the UK. Lancet Infect Dis. 2022; 22(8):1153-1162. PMC: 9300470. DOI: 10.1016/S1473-3099(22)00228-6. View