» Articles » PMID: 39355599

The Usefulness of Cardiopulmonary Exercise Testing to Detect Functional Improvement After Transcatheter Valve Procedures: What Do We Know So Far?

Overview
Authors
Affiliations
Soon will be listed here.
Abstract

Transcatheter valve procedures have become a cornerstone in the management of patients with valvular heart disease and high surgical risk, especially for aortic stenosis and mitral and tricuspid regurgitation. Cardiopulmonary exercise testing (CPET) is generally considered the gold standard for objectively quantifying functional capacity, providing a comprehensive evaluation of the human body's performance, particularly in patients with heart failure (HF). Its accurate assessment is valuable for exploring the pathogenetic mechanisms implicated in HF-related functional impairment. It is also useful for objectively staging the clinical severity and the prognosis of the disease. The improvement in functional capacity after transcatheter valve procedures may be clinically relevant and may provide prognostic information, even in this setting. However, it remains to be fully determined as data on the topic are limited. This review aims to summarize the available evidence on the usefulness of CPET to assess functional improvement in patients undergoing transcatheter valve procedures.

References
1.
Topilsky Y, Maltais S, Inojosa J, Oguz D, Michelena H, Maalouf J . Burden of Tricuspid Regurgitation in Patients Diagnosed in the Community Setting. JACC Cardiovasc Imaging. 2018; 12(3):433-442. DOI: 10.1016/j.jcmg.2018.06.014. View

2.
Kisaka T, Stringer W, Koike A, Agostoni P, Wasserman K . Mechanisms That Modulate Peripheral Oxygen Delivery during Exercise in Heart Failure. Ann Am Thorac Soc. 2017; 14(Supplement_1):S40-S47. DOI: 10.1513/AnnalsATS.201611-889FR. View

3.
Agostoni P, Dumitrescu D . How to perform and report a cardiopulmonary exercise test in patients with chronic heart failure. Int J Cardiol. 2019; 288:107-113. DOI: 10.1016/j.ijcard.2019.04.053. View

4.
Lang C, Agostoni P, Mancini D . Prognostic significance and measurement of exercise-derived hemodynamic variables in patients with heart failure. J Card Fail. 2007; 13(8):672-9. DOI: 10.1016/j.cardfail.2007.05.004. View

5.
Nickenig G, Kowalski M, Hausleiter J, Braun D, Schofer J, Yzeiraj E . Transcatheter Treatment of Severe Tricuspid Regurgitation With the Edge-to-Edge MitraClip Technique. Circulation. 2017; 135(19):1802-1814. DOI: 10.1161/CIRCULATIONAHA.116.024848. View