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Associations Between Sensory Impairment and Functional Limitations Among Older Chinese Adults: Mediating Roles of Social Isolation and Cognition

Overview
Journal BMC Geriatr
Publisher Biomed Central
Specialty Geriatrics
Date 2024 Sep 30
PMID 39350094
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Abstract

Background: The high prevalence of sensory impairment and functional limitations in older adults is a significant concern, yet there is limited understanding of the relationship between these two conditions. Therefore, the objective of this study was to investigate the pathways connecting sensory impairment and functional limitations by examining serial multiple mediating effects of social isolation and cognition in older adults.

Methods: Using the China Health and Retirement Longitudinal Study dataset, a sample of 4871 older adults was selected. The study variables included sensory impairment, functional limitations, social isolation and cognition, and other covariates. A hierarchical multiple linear regression model was used to assess the association between sensory impairment and functional limitations. Mediation analysis was conducted to explore the sequential multiple mediating effects of social isolation and cognitive function in the relationship between sensory impairment and functional limitations.

Results: Our findings revealed a significant and positive association between sensory impairment and functional limitations (B = 0.615, 95% CI: 0.397, 0.834). After adjusting for social isolation and cognitive function, the impact of sensory impairment on functional limitations accounted for 87.19% of the total effect. Additionally, approximately 12.81% of the significant relationship between dual sensory impairment and functional limitations was mediated by social isolation and cognitive function. A serial multiple mediating pathway (sensory impairment → social isolation → cognition → functional limitations) was identified, with a coefficient of 0.013 (95% CI: 0.006, 0.020).

Conclusions: Our study provides evidence for the mediating effects of social isolation and cognition in the relationship between sensory impairment and functional limitations. Given the prevalence of functional limitations among older adults with sensory impairment, it is crucial to consider social isolation and cognitive function in efforts to reduce the burden of disability care. Future validation of these findings through longitudinal studies is necessary.

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References
1.
Steptoe A, Shankar A, Demakakos P, Wardle J . Social isolation, loneliness, and all-cause mortality in older men and women. Proc Natl Acad Sci U S A. 2013; 110(15):5797-801. PMC: 3625264. DOI: 10.1073/pnas.1219686110. View

2.
Zaninotto P, Maharani A, Di Gessa G . Vision and Hearing Difficulties and Life Expectancy Without ADL/IADL Limitations: Evidence From the English Longitudinal Study of Ageing and the Health and Retirement Study. J Gerontol A Biol Sci Med Sci. 2023; 79(2). PMC: 10799758. DOI: 10.1093/gerona/glad136. View

3.
de la Fuente J, Moreno-Agostino D, de la Torre-Luque A, Prina A, Haro J, Caballero F . Development of a Combined Sensory-Cognitive Measure Based on the Common Cause Hypothesis: Heterogeneous Trajectories and Associated Risk Factors. Gerontologist. 2019; 60(5):e357-e366. PMC: 7362620. DOI: 10.1093/geront/gnz066. View

4.
Luo F, Guo L, Thapa A, Yu B . Social isolation and depression onset among middle-aged and older adults in China: Moderating effects of education and gender differences. J Affect Disord. 2021; 283:71-76. DOI: 10.1016/j.jad.2021.01.022. View

5.
Lammer L, Beyer F, Luppa M, Sanders C, Baber R, Engel C . Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study. Elife. 2023; 12. PMC: 10281670. DOI: 10.7554/eLife.83660. View