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Factors Influencing Vaccine Receipt During a 2018 Pediatric Typhoid Conjugate Vaccine Campaign in Navi Mumbai, India

Abstract

In 2018, the Navi Mumbai Municipal Corporation implemented phase 1 of a public sector typhoid conjugate vaccine campaign in Navi Mumbai, India, targeting all children aged 9 months to 14 years within its administrative boundaries. To assess associations with receipt of vaccine in phase 1, we used generalized estimating equations to calculate estimates of vaccination by child-, household-, and community-level demographics (child education and age; household head education, income, and occupation; community informal settlement percent). Campaign vaccine receipt was most associated with children enrolled in school (odds ratio [OR] = 3.84, 95% CI: 2.18-6.77), the lowest household income tertile when divided into three equal parts (OR = 1.64, 95% CI: 1.43-1.84), and lower community-level socioeconomic status (OR = 1.06, 95% CI: 1.04-1.08 per 10% informal settlement proportion). The campaign was successful in reaching the most underserved populations of its target communities.

References
1.
Qadri F, Khanam F, Liu X, Theiss-Nyland K, Biswas P, Bhuiyan A . Protection by vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh: a cluster-randomised trial. Lancet. 2021; 398(10301):675-684. PMC: 8387974. DOI: 10.1016/S0140-6736(21)01124-7. View

2.
Sharma P, Ramakrishnan R, Hutin Y, Manickam P, Gupte M . Risk factors for typhoid in Darjeeling, West Bengal, India: evidence for practical action. Trop Med Int Health. 2009; 14(6):696-702. DOI: 10.1111/j.1365-3156.2009.02283.x. View

3.
. Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2022; 400(10369):2221-2248. PMC: 9763654. DOI: 10.1016/S0140-6736(22)02185-7. View

4.
Da Silva K, Tanmoy A, Pragasam A, Iqbal J, Sajib M, Mutreja A . The international and intercontinental spread and expansion of antimicrobial-resistant Salmonella Typhi: a genomic epidemiology study. Lancet Microbe. 2022; 3(8):e567-e577. PMC: 9329132. DOI: 10.1016/S2666-5247(22)00093-3. View

5.
Hoffman S, LeBoa C, Date K, Haldar P, Harvey P, Shimpi R . Programmatic Effectiveness of a Pediatric Typhoid Conjugate Vaccine Campaign in Navi Mumbai, India. Clin Infect Dis. 2023; 77(1):138-144. PMC: 10320126. DOI: 10.1093/cid/ciad132. View