Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments

Overview

Journal Am J Clin Dermatol

Specialty Dermatology

Date 2024 Sep 30

PMID 39348008

Authors

Yanzhen Pang

William Q Nguyen

Liliana I Guerrero

Lauren P Chrisman

Madeline J Hooper

Morgan C McCarthy

Molly K Hales

Rachel E Lipman

Amy S Paller

Joan Guitart

Xiaolong A Zhou

Affiliations

Soon will be listed here.

Abstract

Erythroderma, an inflammatory skin condition characterized by widespread erythema with variable degrees of exfoliation, pustulation, or vesiculobullous formation, is associated with high morbidity and mortality. Determining the underlying cause of erythroderma frequently presents a diagnostic challenge, which may contribute to the condition's relatively poor prognosis. This review covers the clinical presentation, pathophysiology, diagnosis, and treatment of erythroderma. It discusses similarities and differences among the many underlying etiologies of the condition and differences between erythrodermic and non-erythrodermic presentations of the same dermatosis. Finally, this article explores current research that may provide future tools in the diagnosis and management of erythroderma.

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