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Use of Neuroendoscopy in Combination Treatment of a Three-Year-Old Patient With Primary Disseminated Medulloblastoma: A Case Report

Overview
Journal Cureus
Specialty Biomedical Engineering
Date 2024 Sep 30
PMID 39347241
Authors
Jalolboy A Ashurov
Gerald Musa
Ella V Kumirova
Sirak N Margaryan
Matvey I Livshitz
Sergei S Ozerov
Gervith Reyes Soto
Manuel De Jesus Encarnacion Ramirez
Gennady E Chmutin
Affiliations
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Abstract

A three-year-four-month-old boy with primary disseminated medulloblastoma M3 stage and secondary occlusive hydrocephalus underwent an endoscopic triventriculocisternostomy (ETVC) and tumor biopsy, followed by ventriculoperitoneal shunt (VPS) placement due to ETVC failure. The treatment regimen, which included intensive induction chemotherapy, proton beam therapy (PBT), and maintenance chemotherapy, led to significant clinical improvement and a complete radiological response. Four years post-treatment, the child remains in remission, illustrating the effectiveness of a multimodal approach in managing complex cases of medulloblastoma in pediatric patients.

Citing Articles

Correlation of Edema/Tumor Index With Histopathological Outcomes According to the WHO Classification of Cranial Tumors.

Reyes Soto G, Vega-Moreno D, Catillo-Rangel C, Gonzalez-Aguilar A, Chavez-Martinez O, Nikolenko V Cureus. 2024; 16(11):e72942.

PMID: 39634980 PMC: 11614750. DOI: 10.7759/cureus.72942.

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