Sweet Bell Pepper: A Focus on Its Nutritional Qualities and Illness-Alleviated Properties

Overview

Journal Indian J Clin Biochem

Specialty Biochemistry

Date 2024 Sep 30

PMID 39346723

Authors

Areej Hazem Younes

Yasser Fakri Mustafa

Affiliations

Soon will be listed here.

Abstract

Sweet bell pepper (SBP, L.) can be employed as a spice in many dishes and may also be eaten as a delicious fruit. These two nutritional attributes are owing to the strong, deep taste of many SBP phytochemicals. This fruit has many additional beneficial properties because it contains high concentrations of minerals and vitamins that distinguish it from other kinds of fruits. Almost every part of the SBP is thought to be an excellent source of bioactive substances that are health supporters, such as flavonoids, polyphenols, and various aromatic substances. The ability of SBP-phytochemicals to work as antioxidants, reducing the harmful effects of oxidative stress and consequently preventing many chronic illnesses, is one of their main biomedical characteristics. These phytochemicals have good antibacterial properties, mostly against gram-positive pathogenic microbes, in addition to their anti-carcinogenic and cardio-preventive effects. So, this review aims to highlight the nutritional qualities of SBP-derived phytochemicals and their illness-alleviated characteristics. Antioxidant, anti-inflammatory, antitumor, antidiabetic, and analgesic properties are some of the ones discussed.

References

Ma P, He P, Xu C, Hou B, Qiang G, Du G . Recent developments in natural products for white adipose tissue browning. Chin J Nat Med. 2020; 18(11):803-817. DOI: 10.1016/S1875-5364(20)60021-8. View

Kang J, Tsuyoshi G, Le Ngoc H, Kim H, Tu T, Noh H . Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice. J Med Food. 2011; 14(3):310-5. DOI: 10.1089/jmf.2010.1367. View

Friedman J, Richbart S, Merritt J, Brown K, Denning K, Tirona M . Capsaicinoids: Multiple effects on angiogenesis, invasion and metastasis in human cancers. Biomed Pharmacother. 2019; 118:109317. PMC: 6759410. DOI: 10.1016/j.biopha.2019.109317. View

Wan Z, Shan Z, Geng T, Lu Q, Li L, Yin J . Associations of Moderate Low-Carbohydrate Diets With Mortality Among Patients With Type 2 Diabetes: A Prospective Cohort Study. J Clin Endocrinol Metab. 2022; 107(7):e2702-e2709. DOI: 10.1210/clinem/dgac235. View

Cortes-Ferre H, Antunes-Ricardo M, Gutierrez-Uribe J . Enzyme-assisted extraction of anti-inflammatory compounds from habanero chili pepper () seeds. Front Nutr. 2022; 9:942805. PMC: 9498820. DOI: 10.3389/fnut.2022.942805. View

Basith S, Cui M, Hong S, Choi S . Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases. Molecules. 2016; 21(8). PMC: 6272969. DOI: 10.3390/molecules21080966. View

Zhang W, Zhang Q, Wang L, Zhou Q, Wang P, Qing Y . The effects of capsaicin intake on weight loss among overweight and obese subjects: a systematic review and meta-analysis of randomised controlled trials. Br J Nutr. 2023; 130(9):1645-1656. DOI: 10.1017/S0007114523000697. View

Lee G, Shin M, Yoon D, Kim A, Yu R, Park N . Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice. Obesity (Silver Spring). 2013; 21(1):115-22. DOI: 10.1002/oby.20246. View

Chavez-Mendoza C, Sanchez E, Carvajal-Millan E, Munoz-Marquez E, Guevara-Aguilar A . Characterization of the nutraceutical quality and antioxidant activity in bell pepper in response to grafting. Molecules. 2013; 18(12):15689-703. PMC: 6270167. DOI: 10.3390/molecules181215689. View

10.

Mokhtar M, Ginestra G, Youcefi F, Filocamo A, Bisignano C, Riazi A . Antimicrobial Activity of Selected Polyphenols and Capsaicinoids Identified in Pepper (Capsicum annuum L.) and Their Possible Mode of Interaction. Curr Microbiol. 2017; 74(11):1253-1260. DOI: 10.1007/s00284-017-1310-2. View

11.

Zhao J, Hu Y, Huang C, Ma X, Kang C, Zhang Y . Dihydrocapsaicin suppresses proinflammatory cytokines expression by enhancing nuclear factor IA in a NF-κB-dependent manner. Arch Biochem Biophys. 2016; 604:27-35. DOI: 10.1016/j.abb.2016.06.002. View

12.

Wang Y, Zhao J, Jiang L, Mu Y . The Application of Skin Care Product in Melasma Treatment. Clin Cosmet Investig Dermatol. 2021; 14:1165-1171. PMC: 8435474. DOI: 10.2147/CCID.S323748. View

13.

Gupta S, Khushboo , Gupta V, Minhas U, Kumar R, Sharma B . Euglena Species: Bioactive Compounds and their Varied Applications. Curr Top Med Chem. 2021; 21(29):2620-2633. DOI: 10.2174/1568026621666210813111424. View

14.

Hazekawa M, Hideshima Y, Ono K, Nishinakagawa T, Kawakubo-Yasukochi T, Takatani-Nakase T . Anti-inflammatory effects of water extract from bell pepper (. var. ) leaves . Exp Ther Med. 2017; 14(5):4349-4355. PMC: 5658767. DOI: 10.3892/etm.2017.5106. View

15.

Suwannaphet W, Meeprom A, Yibchok-anun S, Adisakwattana S . Preventive effect of grape seed extract against high-fructose diet-induced insulin resistance and oxidative stress in rats. Food Chem Toxicol. 2010; 48(7):1853-7. DOI: 10.1016/j.fct.2010.04.021. View

16.

Ramos-Tovar E, Muriel P . Free radicals, antioxidants, nuclear factor-E2-related factor-2 and liver damage. J Appl Toxicol. 2019; 40(1):151-168. DOI: 10.1002/jat.3880. View

17.

Sharma M, Usmani Z, Gupta V, Bhat R . Valorization of fruits and vegetable wastes and by-products to produce natural pigments. Crit Rev Biotechnol. 2021; 41(4):535-563. DOI: 10.1080/07388551.2021.1873240. View

18.

Shukla S, Mehta A, John J, Singh S, Mehta P, Vyas S . Antioxidant activity and total phenolic content of ethanolic extract of Caesalpinia bonducella seeds. Food Chem Toxicol. 2009; 47(8):1848-51. DOI: 10.1016/j.fct.2009.04.040. View

19.

Akullo J, Kiage-Mokua B, Nakimbugwe D, Nganga J, Kinyuru J . Phytochemical profile and antioxidant activity of various solvent extracts of two varieties of ginger and garlic. Heliyon. 2023; 9(8):e18806. PMC: 10412845. DOI: 10.1016/j.heliyon.2023.e18806. View

20.

Halliwell B . Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiol. 2006; 141(2):312-22. PMC: 1475431. DOI: 10.1104/pp.106.077073. View