» Articles » PMID: 39344432

Ethical Considerations on the Moral Status of the Embryo and Embryo-like Structures†

Overview
Journal Hum Reprod
Date 2024 Sep 30
PMID 39344432
Authors
Affiliations
Soon will be listed here.
Abstract

The current article provides an ethical reflection on the moral status of the human embryo, which is a crucial factor in determining permissible actions involving embryos and the extent of their protection. It advocates for the extension of the research period for embryos to 28-days post fertilization. It also states that integrated embryo-like structures (ELSs) should not currently be given the same moral status as natural embryos. However, if they pass the relevant tests, they should be subject to the same rules as natural embryos.

Citing Articles

20 Years Since the Enactment of Italian Law No. 40/2004 on Medically Assisted Procreation: How It Has Changed and How It Could Change.

Vergallo G, Marinelli S, Napoletano G, De Paola L, Treglia M, Zaami S Int J Environ Res Public Health. 2025; 22(2).

PMID: 40003521 PMC: 11855168. DOI: 10.3390/ijerph22020296.

References
1.
Appleby J, Bredenoord A . Should the 14-day rule for embryo research become the 28-day rule?. EMBO Mol Med. 2018; 10(9). PMC: 6127884. DOI: 10.15252/emmm.201809437. View

2.
Devolder K . Human embryonic stem cell research: why the discarded-created-distinction cannot be based on the potentiality argument. Bioethics. 2005; 19(2):167-86. DOI: 10.1111/j.1467-8519.2005.00432.x. View

3.
Pennings G . IVF embryos in the bin, embryo-like structures in the spotlight. Reprod Biomed Online. 2024; 48(6):103886. DOI: 10.1016/j.rbmo.2024.103886. View

4.
Yu L, Wei Y, Duan J, Schmitz D, Sakurai M, Wang L . Blastocyst-like structures generated from human pluripotent stem cells. Nature. 2021; 591(7851):620-626. DOI: 10.1038/s41586-021-03356-y. View

5.
Liu X, Tan J, Schroder J, Aberkane A, Ouyang J, Mohenska M . Modelling human blastocysts by reprogramming fibroblasts into iBlastoids. Nature. 2021; 591(7851):627-632. DOI: 10.1038/s41586-021-03372-y. View