Differences in PCV13 Recommendation Practices Between Pediatric Care Providers and Primary Care Providers in China: A Cross-Sectional Survey of Behavior and Social Drivers

Overview

Journal Vaccines (Basel)

Date 2024 Sep 28

PMID 39340112

Authors

Yuan Dang

Lin Wang

Yuming Liu

Boyan Wang

Huiwen Deng

Can Ye

Chunping Wang

Yangmu Huang

Affiliations

Soon will be listed here.

Abstract

This study examines the recommendation behaviors and influencing factors for the 13-valent Pneumococcal Conjugate Vaccine (PCV13) among 3579 Chinese healthcare workers (HCWs), including 1775 pediatric care providers (Peds-PCPs) and 1804 primary care providers (PCPs). Data were collected from May to July 2023 through a national cross-sectional survey using a structured questionnaire, distributed across hospitals providing pediatric services in five provincial-level administrative divisions. The sociodemographic data, vaccine knowledge, and recommendation practices were analyzed using Pearson's chi-square test, Wilcoxson rank-sum test, and multivariate logistic regression. Results show that while PCPs are more likely to recommend PCV13, vaccine hesitancy persists among Peds-PCPs. Logistic regression revealed that higher influenza vaccination intention, salary, vaccine consultation frequency, familiarity with immunization, work ethic, and flexible schedules positively impacted HCWs' recommendation behavior. Factors influencing Peds-PCPs' recommendations include vaccine training (OR: 1.470, CI: 1.049-2.509), safety recognition (OR: 1.986, CI: 1.163-3.391), concern over rejection (OR = 1.274, CI: 1.076-1.508) and vaccine cost (OR = 1.203, CI: 1.023-1.414). For PCPs, influencing factors were the perceived susceptibility of children to pneumonia (OR = 2.185, CI: 1.074-4.445), acceptance of herd immunity (OR: 1.717, CI: 1.101-2.677), and belief that parents with better family conditions are more likely to accept vaccine recommendations (OR = 1.229, CI: 1.024-1.477). This survey underscores the need for tailored interventions to address differing perceptions and enhance confidence in the safety and efficacy of vaccines among HCWs, particularly Peds-PCPs.

References

Liu L, Zhang Z, Zhang X, Xu C, Song Y, Li L . Coverage of 13-Valent Pneumococcal Conjugate Vaccine Among Children 0-15 Months of Age - 9 Provinces, China, 2019-2021. China CDC Wkly. 2023; 5(17):379-384. PMC: 10184383. DOI: 10.46234/ccdcw2023.072. View

Kaur M, Coppeta L, Olesen O . Vaccine Hesitancy among Healthcare Workers in Europe: A Systematic Review. Vaccines (Basel). 2023; 11(11). PMC: 10675787. DOI: 10.3390/vaccines11111657. View

OBrien K, Wolfson L, Watt J, Henkle E, Deloria-Knoll M, McCall N . Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet. 2009; 374(9693):893-902. DOI: 10.1016/S0140-6736(09)61204-6. View

Davies B, Olivier J, Amponsah-Dacosta E . Health Systems Determinants of Delivery and Uptake of Maternal Vaccines in Low- and Middle-Income Countries: A Qualitative Systematic Review. Vaccines (Basel). 2023; 11(4). PMC: 10144938. DOI: 10.3390/vaccines11040869. View

Eller N, Henrikson N, Opel D . Vaccine Information Sources and Parental Trust in Their Child's Health Care Provider. Health Educ Behav. 2019; 46(3):445-453. PMC: 7872219. DOI: 10.1177/1090198118819716. View

Oyo-Ita A, Oduwole O, Arikpo D, Effa E, Esu E, Balakrishna Y . Interventions for improving coverage of childhood immunisation in low- and middle-income countries. Cochrane Database Syst Rev. 2023; 12:CD008145. PMC: 10698843. DOI: 10.1002/14651858.CD008145.pub4. View

Lyu Y, Lai X, Ma Y, Fang H . Factors associated with recommendation behaviors of four non-National Immunization Program vaccines: a cross-sectional survey among public health workers in China. Infect Dis Poverty. 2023; 12(1):91. PMC: 10559509. DOI: 10.1186/s40249-023-01142-8. View

Jiang B, Cao Y, Qian J, Jiang M, Huang Q, Sun Y . Healthcare Workers' Attitudes toward Influenza Vaccination: A Behaviour and Social Drivers Survey. Vaccines (Basel). 2023; 11(1). PMC: 9863509. DOI: 10.3390/vaccines11010143. View

Lai X, Wahl B, Yu W, Xu T, Zhang H, Garcia C . National, regional, and provincial disease burden attributed to and type b in children in China: Modelled estimates for 2010-17. Lancet Reg Health West Pac. 2022; 22:100430. PMC: 8928075. DOI: 10.1016/j.lanwpc.2022.100430. View

10.

Sharma N, Harris E, Lloyd J, Mistry S, Harris M . Community health workers involvement in preventative care in primary healthcare: a systematic scoping review. BMJ Open. 2019; 9(12):e031666. PMC: 6937114. DOI: 10.1136/bmjopen-2019-031666. View

11.

Li B, Chen J . Barriers to community healthcare delivery in urban China: a nurse perspective. Int J Qual Stud Health Well-being. 2023; 18(1):2220524. PMC: 10259341. DOI: 10.1080/17482631.2023.2220524. View

12.

Larson H, Clarke R, Jarrett C, Eckersberger E, Levine Z, Schulz W . Measuring trust in vaccination: A systematic review. Hum Vaccin Immunother. 2018; 14(7):1599-1609. PMC: 6067893. DOI: 10.1080/21645515.2018.1459252. View

13.

Scelfo C, Menzella F, Fontana M, Ghidoni G, Galeone C, Facciolongo N . Pneumonia and Invasive Pneumococcal Diseases: The Role of Pneumococcal Conjugate Vaccine in the Era of Multi-Drug Resistance. Vaccines (Basel). 2021; 9(5). PMC: 8145843. DOI: 10.3390/vaccines9050420. View

14.

Karafillakis E, Larson H . The paradox of vaccine hesitancy among healthcare professionals. Clin Microbiol Infect. 2018; 24(8):799-800. DOI: 10.1016/j.cmi.2018.04.001. View

15.

Muhoza P, Danovaro-Holliday M, Diallo M, Murphy P, Sodha S, Requejo J . Routine Vaccination Coverage - Worldwide, 2020. MMWR Morb Mortal Wkly Rep. 2021; 70(43):1495-1500. PMC: 8553029. DOI: 10.15585/mmwr.mm7043a1. View

16.

. Pneumococcal conjugate vaccine for childhood immunization--WHO position paper. Wkly Epidemiol Rec. 2007; 82(12):93-104. View