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Removal of Tibial Marrow Induces Increased Formation of Bone and Cartilage in Rat Mandibular Condyle

Overview
Journal Calcif Tissue Int
Specialty Pathology
Date 1985 Sep 1
PMID 3933795
Citations 8
Authors
I Bab
D Gazit
A Massarawa
J Sela
Affiliations
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Abstract

The present paper reports alterations in osteogenesis recorded in mandibular condyles 3-18 days after the removal of marrow tissue from tibial bones. Computerized histomorphometric evaluation of undecalcified condyles revealed a considerable increase in the thickness of condylar cartilage, in particular, the zone of provisional calcification. Measurements of the subcartilaginous trabecular bone suggested an increase in the number of osteoblasts and in their activity. The systemic enhancement of osteogenesis may be initiated by circulating factors released at the affected limb during regeneration of the marrow.

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