Organizational Challenges for Partial Heart Transplantation

Overview

Journal Future Cardiol

Specialty Cardiology & Vascular Diseases

Date 2024 Sep 27

PMID 39330872

Authors

Vincent S Alexander

Andrew D Vogel

Zachary T Silvano

Herra Javed

Alekhya Mitta

Taufiek Konrad Rajab

Affiliations

Soon will be listed here.

Abstract

Partial heart transplantation (PHT) has emerged as a new treatment strategy to correct unrepairable heart valve dysfunction in pediatric patients. PHT selectively replaces the dysfunctional components of the recipient's heart and spares the native ventricles. As a result, the transplant biology of PHTs differs from heart transplants. Notably, donor hearts that are unsuitable for whole heart transplantation can be used, graft preservation can be prolonged and immunosuppression levels can be lowered. These nuances of PHT transplant biology have important implications for organizational aspects of PHT clinical application.

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