Efficacy of 1060 Nm Diode Laser for Non-Invasive Subcutaneous Fat Reduction in Mini-Pigs

Overview

Journal Clin Cosmet Investig Dermatol

Publisher Dove Medical Press

Specialty Dermatology

Date 2024 Sep 25

PMID 39318477

Authors

Yea-Jin Lee

Namgue Hong

Eun Seo Choi

Sun-Hyang Choi

Eun Young Kim

Hyeong Ju Park

Jin-Chul Ahn

Affiliations

Soon will be listed here.

Abstract

Purpose: To evaluate the efficacy and safety of abdominal fat reduction in mini-pigs, utilizing at 1060 nm diode laser with a wavelength of 1060 nm.

Patients And Methods: The laser system non-invasively disrupts adipose tissue; its effectiveness and safety were evaluated by ultrasound imaging and histological analysis. Laser irradiation was performed with various powers, and the cooling function was activated to prevent skin surface damage.

Results: The dermal tissue temperature increased to at least 43°C during laser exposure, leading to a decrease in abdominal fat thickness after 30 days. Blood tests revealed no significant changes in kidney and liver function but showed increased blood levels of nonessential free acids (NEFAs), likely due to the release of fatty tissue-derived free fatty acids. Histological evaluation demonstrated rapid transformation of adipose tissue into collagen, muscle fibers, and intracellular fibrous tissue.

Conclusion: The 1060 nm laser showed promise as a non-invasive and safe tool for reducing abdominal fat.

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