Enhancing Biocompatibility of the Brain-machine Interface: A Review

Overview

Journal Bioact Mater

Specialty Biomedical Engineering

Date 2024 Sep 23

PMID 39308547

Authors

Jordan Villa

Joaquin Cury

Lexie Kessler

Xiaodong Tan

Claus-Peter Richter

Affiliations

Soon will be listed here.

Abstract

In vivo implantation of microelectrodes opens the door to studying neural circuits and restoring damaged neural pathways through direct electrical stimulation and recording. Although some neuroprostheses have achieved clinical success, electrode material properties, inflammatory response, and glial scar formation at the electrode-tissue interfaces affect performance and sustainability. Those challenges can be addressed by improving some of the materials' mechanical, physical, chemical, and electrical properties. This paper reviews materials and designs of current microelectrodes and discusses perspectives to advance neuroprosthetics performance.

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