Management of Complications in Patients with an Ileostomy: an Umbrella Review of Systematic Reviews for the EndOTrial Consortium

Overview

Journal Int J Colorectal Dis

Specialties Gastroenterology
General Surgery

Date 2024 Sep 20

PMID 39304546

Authors

Virginia Solitano

Sudheer Kumar Vuyyuru

Yuhong Yuan

Siddharth Singh

Neeraj Narula

Christopher Ma

Jurij Hanzel

Megan Hutton

Julie Ann Van Koughnett

Florian Rieder

Vipul Jairath

Affiliations

Soon will be listed here.

Abstract

Background: Standardized clinical care processes for patients with Crohn's disease (CD) and a permanent ileostomy (PI) are lacking. The EndOTrial consortium aims to address this gap by developing pathways for care.

Methods: In this umbrella review, we searched major databases for relevant systematic reviews (SRs) or scoping reviews (ScR) published until January 5, 2024. Screening, data extraction, and quality appraisal (AMSTAR 2) were performed by two independent reviewers.

Results: Of 1349 screened papers, 22 reviews met our inclusion criteria, including 20 SRs (eight with meta-analysis) and 2 ScRs. None exclusively focused on PI. Furthermore, nine reviews did not mention patients with inflammatory bowel disease (IBD), and only two reviews included patients with high-output ileostomy, highlighting a large evidence gap. The identified reviews covered six categories with nine types of interventions, including ostomy care pathways, peristomal skin care, patient education, clinical management of high-output stoma, management and prevention of postoperative ileus, dietary and nutritional support, nursing and supporting care, telemedicine, and self-management interventions. Most SRs including nursing interventions for stoma care highlighted nurses' role in a variety of standard and specialized treatments. Notably, none of the reviews exclusively examined disease recurrence, stoma pouching systems or adhesives, behavioral interventions, or mental health in patients living with ileostomy.

Conclusions: Evidence for best practice interventions to treat complications and improve quality of life in patients living with an ileostomy for CD is limited and heterogeneous. These results outline the need for standardized clinical care processes and pathways tailored to the unique needs of this patient population.

Citing Articles

Successful Re-ileostomy Using Skin Flap Formation Techniques.

Matsuki H, Oura S, Kataoka N Cureus. 2025; 16(12):e74940.

PMID: 39744268 PMC: 11688590. DOI: 10.7759/cureus.74940.

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