Pregabalin-Induced Bullous Pemphigoid: A Case Report of a Rare Drug-Triggered Autoimmune Skin Disorder
Overview
Overview
Authors
Affiliations
Affiliations
Soon will be listed here.
Abstract
Bullous pemphigoid (BP) is a common autoimmune blistering disorder primarily affecting the elderly, characterized by intense pruritus and tense bullae on the skin. We report the case of a 75-year-old female with a history of breast cancer who developed BP on both feet following the initiation of pregabalin for pain management. Histopathological examination confirmed BP, and symptoms improved with topical corticosteroid treatment and discontinuation of pregabalin. This case highlights the potential of pregabalin to induce BP and underscores the importance of recognizing medication-induced bullous diseases for prompt diagnosis and management.
References
1.
Toth C
. Pregabalin: latest safety evidence and clinical implications for the management of neuropathic pain. Ther Adv Drug Saf. 2014; 5(1):38-56.
PMC: 4110876.
DOI: 10.1177/2042098613505614.
View
2.
Chu K, Yu H, Yu S
. Current and Innovated Managements for Autoimmune Bullous Skin Disorders: An Overview. J Clin Med. 2022; 11(12).
PMC: 9224787.
DOI: 10.3390/jcm11123528.
View
3.
Kridin K, Ludwig R
. The Growing Incidence of Bullous Pemphigoid: Overview and Potential Explanations. Front Med (Lausanne). 2018; 5:220.
PMC: 6109638.
DOI: 10.3389/fmed.2018.00220.
View
4.
Khalid S, Khan Z, Ali M, Almas T, Khedro T, Raj Nagarajan V
. A blistering new era for bullous pemphigoid: A scoping review of current therapies, ongoing clinical trials, and future directions. Ann Med Surg (Lond). 2021; 70:102799.
PMC: 8435812.
DOI: 10.1016/j.amsu.2021.102799.
View
5.
Deotto M, Spiller A, Sernicola A, Alaibac M
. Bullous pemphigoid: An immune disorder related to aging (Review). Exp Ther Med. 2021; 23(1):50.
PMC: 8652395.
DOI: 10.3892/etm.2021.10972.
View