Bibliometric Analysis of Publications That Cited the CIOMS 2016 "International Ethical Guidelines for Health-related Research Involving Humans"

Overview

Journal Heliyon

Specialty Social Sciences

Date 2024 Sep 16

PMID 39281646

Authors

Robin Haunschild

Joanne Kays

Lembit Rago

Mark Kays

Affiliations

Soon will be listed here.

Abstract

The CIOMS book "International Ethical Guidelines for Health-related Research Involving Humans", published in 2016 (IEG2016), provides information to assist research ethics committee members and research practitioners with pragmatically implementing ethical considerations while planning and conducting their research. To identify which aspects of research IEG2016 has had the greatest impact since its publication, we analyzed metadata from 942 papers that cited IEG2016 (English language title only) from Web of Science (WoS, Clarivate). Using VOSviewer, we mapped the co-occurrence of keywords to derive the network of all keywords that co-occurred at least five times in the set of citing papers. We found that the keywords , , , and had high co-occurrence scores in this set of publications. Strong links were also observed between , , and . We identified fifteen human-related (HR) keyword nodes in this keyword network. Analysis of the subset of 273 IEG2016-citing articles containing these fifteen HR keywords showed later-date publications were focused on the youngest humans (, , , ) and the humans typically responsible for those youngest humans, namely and . Seventy-nine of the 110 networked countries/regions associated with IEG2016-citing articles were home to HR keyword articles. We conclude that IEG2016 has had significant impact in health and medical science literature and has served as a foundation for health-related research around the world in the areas of , , and and the linkage of these topics to under-represented populations in such research.

Citing Articles

Dilemmas of Ethics in Practice in Longitudinal Health Research: Identifying Opportunities for Widening Participation of Residents.

Twine R, Hundt G, Kahn K Front Sociol. 2021; 4:33.

PMID: 33869357 PMC: 8022611. DOI: 10.3389/fsoc.2019.00033.

Assessment of Parents'/Guardians' Initial Comprehension and 1-Day Recall of Elements of Informed Consent Within a Mozambican Study of Pediatric Bacteremia.

Ossemane E, Moon T, Sacarlal J, Sevene E, Kenga D, Gong W J Empir Res Hum Res Ethics. 2018; 13(3):247-257.

PMID: 29667543 PMC: 5993589. DOI: 10.1177/1556264618767780.

References

Hickey G, Porter K, Tembo D, Rennard U, Tholanah M, Beresford P . What Does "Good" Community and Public Engagement Look Like? Developing Relationships With Community Members in Global Health Research. Front Public Health. 2022; 9:776940. PMC: 8830293. DOI: 10.3389/fpubh.2021.776940. View

Gooding K, Phiri M, Peterson I, Parker M, Desmond N . Six dimensions of research trial acceptability: how much, what, when, in what circumstances, to whom and why?. Soc Sci Med. 2018; 213:190-198. PMC: 7614255. DOI: 10.1016/j.socscimed.2018.07.040. View

Mackworth-Young C, Schneiders M, Wringe A, Simwinga M, Bond V . Navigating 'ethics in practice': An ethnographic case study with young women living with HIV in Zambia. Glob Public Health. 2019; 14(12):1689-1702. DOI: 10.1080/17441692.2019.1616799. View

Canario Guzman J, Orlich J, Mendizabal-Cabrera R, Ying A, Verges C, Espinoza E . Strengthening research ethics governance and regulatory oversight in Central America and the Dominican Republic in response to the COVID-19 pandemic: a qualitative study. Health Res Policy Syst. 2022; 20(1):138. PMC: 9786418. DOI: 10.1186/s12961-022-00933-z. View

van der Graaf R, van der Zande I, den Ruijter H, Oudijk M, van Delden J, Oude Rengerink K . Fair inclusion of pregnant women in clinical trials: an integrated scientific and ethical approach. Trials. 2018; 19(1):78. PMC: 5789693. DOI: 10.1186/s13063-017-2402-9. View

Sansom L, Minh T, Hill I, Nguyen Than Ha Q, Trong T, Vidaillac C . Towards a fair and transparent research participant compensation and reimbursement framework in Vietnam. Int Health. 2020; 12(6):533-540. PMC: 7651161. DOI: 10.1093/inthealth/ihaa066. View

Singh J . Informed consent and community engagement in open field research: lessons for gene drive science. BMC Med Ethics. 2019; 20(1):54. PMC: 6660705. DOI: 10.1186/s12910-019-0389-3. View

Ries N, Mansfield E, Sanson-Fisher R . Ethical and legal aspects of research involving older people with cognitive impairment: A survey of dementia researchers in Australia. Int J Law Psychiatry. 2020; 68:101534. DOI: 10.1016/j.ijlp.2019.101534. View

Wilkinson A, Slack C, Thabethe S, Salzwedel J . "": Can Ethics Review Help Address the "3 Ts" of Tokenism, Toxicity, and Tailoring in Stakeholder Engagement?. J Empir Res Hum Res Ethics. 2022; 17(3):292-303. PMC: 9136363. DOI: 10.1177/15562646221078415. View

10.

Nkosi B, Zanoni B, Seeley J, Strode A . The ethical-legal requirements for adolescent self-consent to research in sub-Saharan Africa: A scoping review. Bioethics. 2021; 36(5):576-586. DOI: 10.1111/bioe.12988. View

11.

Shah S, London A, Mofenson L, Lavery J, John-Stewart G, Flynn P . Ethically designing research to inform multidimensional, rapidly evolving policy decisions: Lessons learned from the PROMISE HIV Perinatal Prevention Trial. Clin Trials. 2021; 18(6):681-689. PMC: 9015017. DOI: 10.1177/17407745211045734. View

12.

. Declaration of Helsinki. Ethical principles for medical research involving human subjects. J Indian Med Assoc. 2009; 107(6):403-5. View

13.

Mbo F, Mutombo W, Ngolo D, Kabangu P, Valverde Mordt O, Strub Wourgaft N . How Clinical Research Can Contribute to Strengthening Health Systems in Low Resource Countries. Trop Med Infect Dis. 2020; 5(2). PMC: 7345178. DOI: 10.3390/tropicalmed5020048. View

14.

Borgeat Meza M, Luengo-Charath X, Arancibia M, Madrid E . Council for International Organizations of Medical Sciences (CIOMS) Ethical Guidelines: advancements and unsolved topics in 2016 upgrade. Medwave. 2018; 18(2):e7208. DOI: 10.5867/medwave.2018.02.7208. View

15.

Dalpe G, Thorogood A, Knoppers B . A Tale of Two Capacities: Including Children and Decisionally Vulnerable Adults in Biomedical Research. Front Genet. 2019; 10:289. PMC: 6459892. DOI: 10.3389/fgene.2019.00289. View

16.

Tindana P, Molyneux S, Bull S, Parker M . 'It is an entrustment': Broad consent for genomic research and biobanks in sub-Saharan Africa. Dev World Bioeth. 2017; 19(1):9-17. PMC: 6624131. DOI: 10.1111/dewb.12178. View

17.

Munung N, Nembaware V, Osei-Tutu L, Treadwell M, Chide O, Bukini D . Assent, parental consent and reconsent for health research in Africa: thematic analysis of national guidelines and lessons from the SickleInAfrica registry. BMC Med Ethics. 2022; 23(1):130. PMC: 9730625. DOI: 10.1186/s12910-022-00843-3. View

18.

Ward C, Shaw D, Sprumont D, Sankoh O, Tanner M, Elger B . Good collaborative practice: reforming capacity building governance of international health research partnerships. Global Health. 2018; 14(1):1. PMC: 5759302. DOI: 10.1186/s12992-017-0319-4. View

19.

Roest J, Nkosi B, Seeley J, Molyneux S, Kelley M . Respecting relational agency in the context of vulnerability: What can research ethics learn from the social sciences?. Bioethics. 2023; 37(4):379-388. PMC: 10946974. DOI: 10.1111/bioe.13139. View

20.

Slack C, Wilkinson A, Salzwedel J, Ndebele P . Strengthening stakeholder engagement through ethics review in biomedical HIV prevention trials: opportunities and complexities. J Int AIDS Soc. 2018; 21 Suppl 7:e25172. PMC: 6193317. DOI: 10.1002/jia2.25172. View