The Correlation of Global Burden of Vision Impairment and Ambient Atmospheric Fine Particulate Matter

Overview

Journal J Curr Ophthalmol

Date 2024 Sep 16

PMID 39281396

Authors

Parya Abdolalizadeh

Khalil Ghasemi Falavarjani

Affiliations

Soon will be listed here.

Abstract

Purpose: To assess the correlation between the worldwide burden of vision impairment (VI) and fine particulate matter (PM) 2.5.

Methods: In this retrospective cross-sectional study, global and national prevalence and disability-adjusted lost year (DALY) numbers and rates of total VI, glaucoma, cataract, and age-related macular degeneration (AMD) were obtained from the Global Burden of Disease database. The global and national levels of PM2.5 levels were also extracted. The main outcome measures were the correlation of PM2.5 levels with total VI and three ocular diseases in different age, sex, and socioeconomic subgroups.

Results: In 2019, the worldwide prevalence of total VI and exposure level of PM2.5 was 9.6% (95% uncertainty interval: 8.0-11.3) and 42.5 μg/m, respectively. The national age-standardized prevalence rates of total VI ( = 0.52, < 0.001), glaucoma ( = 0.65, < 0.001), AMD ( = 0.67, < 0.001), and cataract ( = 0.44, < 0.001) have a positive correlation with PM2.5 levels. In addition, the national age-standardized DALY rates of total VI ( = 0.62, < 0.001), glaucoma ( = 0.62, < 0.001), AMD ( = 0.54, < 0.001), and cataract ( = 0.45, < 0.001) significantly correlated with PM2.5 levels. The correlations remained significant in different age, sex, and sociodemographic subgroups.

Conclusion: National prevalence rates of VI and three major ocular diseases correlate significantly with PM2.5 exposure levels, worldwide.

References

Shin J, Lee H, Kim H . Association between Exposure to Ambient Air Pollution and Age-Related Cataract: A Nationwide Population-Based Retrospective Cohort Study. Int J Environ Res Public Health. 2020; 17(24). PMC: 7763970. DOI: 10.3390/ijerph17249231. View

West S, Bates M, Lee J, Schaumberg D, Lee D, Adair-Rohani H . Is household air pollution a risk factor for eye disease?. Int J Environ Res Public Health. 2013; 10(11):5378-98. PMC: 3863851. DOI: 10.3390/ijerph10115378. View

Wang W, He M, Li Z, Huang W . Epidemiological variations and trends in health burden of glaucoma worldwide. Acta Ophthalmol. 2019; 97(3):e349-e355. DOI: 10.1111/aos.14044. View

Seaton A, MacNee W, Donaldson K, Godden D . Particulate air pollution and acute health effects. Lancet. 1995; 345(8943):176-8. DOI: 10.1016/s0140-6736(95)90173-6. View

Izzotti A, Bagnis A, Sacca S . The role of oxidative stress in glaucoma. Mutat Res. 2006; 612(2):105-14. DOI: 10.1016/j.mrrev.2005.11.001. View

Di Q, Wang Y, Zanobetti A, Wang Y, Koutrakis P, Choirat C . Air Pollution and Mortality in the Medicare Population. N Engl J Med. 2017; 376(26):2513-2522. PMC: 5766848. DOI: 10.1056/NEJMoa1702747. View

Vijaya L, George R, Baskaran M, Arvind H, Raju P, Ramesh S . Prevalence of primary open-angle glaucoma in an urban south Indian population and comparison with a rural population. The Chennai Glaucoma Study. Ophthalmology. 2007; 115(4):648-654.e1. DOI: 10.1016/j.ophtha.2007.04.062. View

Lambert N, Elshelmani H, Singh M, Mansergh F, Wride M, Padilla M . Risk factors and biomarkers of age-related macular degeneration. Prog Retin Eye Res. 2016; 54:64-102. PMC: 4992630. DOI: 10.1016/j.preteyeres.2016.04.003. View

Banerjee A, Mondal N, Das D, Ray M . Neutrophilic inflammatory response and oxidative stress in premenopausal women chronically exposed to indoor air pollution from biomass burning. Inflammation. 2011; 35(2):671-83. DOI: 10.1007/s10753-011-9360-2. View

10.

Brook R, Rajagopalan S, Pope 3rd C, Brook J, Bhatnagar A, Diez-Roux A . Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation. 2010; 121(21):2331-78. DOI: 10.1161/CIR.0b013e3181dbece1. View

11.

Jarrett S, Boulton M . Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med. 2012; 33(4):399-417. PMC: 3392472. DOI: 10.1016/j.mam.2012.03.009. View

12.

Cohen A, Brauer M, Burnett R, Anderson H, Frostad J, Estep K . Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015. Lancet. 2017; 389(10082):1907-1918. PMC: 5439030. DOI: 10.1016/S0140-6736(17)30505-6. View

13.

Clougherty J . A growing role for gender analysis in air pollution epidemiology. Environ Health Perspect. 2010; 118(2):167-76. PMC: 2831913. DOI: 10.1289/ehp.0900994. View

14.

Sun H, Luo C, Chiang Y, Yeh K, Li Y, Ho Y . Association Between PM Exposure Level and Primary Open-Angle Glaucoma in Taiwanese Adults: A Nested Case-Control Study. Int J Environ Res Public Health. 2021; 18(4). PMC: 7916685. DOI: 10.3390/ijerph18041714. View

15.

Sorensen M, Daneshvar B, Hansen M, Dragsted L, Hertel O, Knudsen L . Personal PM2.5 exposure and markers of oxidative stress in blood. Environ Health Perspect. 2003; 111(2):161-6. PMC: 1241344. DOI: 10.1289/ehp.111-1241344. View

16.

Liu F, Huang Y, Zhang F, Chen Q, Wu B, Rui W . Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. J Neurochem. 2015; 134(2):315-26. PMC: 4709176. DOI: 10.1111/jnc.13135. View

17.

Zanobetti A, Schwartz J, Dockery D . Airborne particles are a risk factor for hospital admissions for heart and lung disease. Environ Health Perspect. 2000; 108(11):1071-7. PMC: 1240165. DOI: 10.1289/ehp.001081071. View

18.

Choi Y, Park S, Paik H, Kim M, Wee W, Kim D . Unexpected potential protective associations between outdoor air pollution and cataracts. Environ Sci Pollut Res Int. 2018; 25(11):10636-10643. DOI: 10.1007/s11356-018-1266-1. View

19.

Cheng H, Pan R, Yeh H, Lai K, Yen M, Chan C . Ambient Air Pollution and the Risk of Central Retinal Artery Occlusion. Ophthalmology. 2016; 123(12):2603-2609. DOI: 10.1016/j.ophtha.2016.08.046. View

20.

Beebe D, Holekamp N, Shui Y . Oxidative damage and the prevention of age-related cataracts. Ophthalmic Res. 2010; 44(3):155-65. PMC: 2952186. DOI: 10.1159/000316481. View