Stellate Ganglion Blocks for Post-Traumatic Stress Disorder: A Review of Mechanisms, Efficacy, and Complications

Overview

Journal Psychopharmacol Bull

Specialty Pharmacology

Date 2024 Sep 12

PMID 39263203

Authors

Jamal Hasoon

Sana Sultana

Aila Malik

Patrick Brown

Alexa Ryder

Christopher L Robinson

Ivan Urits

Giustino Varrassi

Omar Viswanath

Affiliations

Soon will be listed here.

Abstract

Post-traumatic stress disorder (PTSD) stands as a pervasive psychiatric condition, exerting a profound impact on millions across the globe. Despite the availability of traditional therapeutic modalities, many individuals continue to grapple with suboptimal treatment outcomes, underscoring the urgent need for novel interventions. In recent years, stellate ganglion blocks (SGBs) have garnered attention as a promising avenue in the treatment landscape for PTSD, showcasing remarkable efficacy in ameliorating symptomatology and enhancing overall quality of life. This comprehensive review seeks to delve into the current landscape of research surrounding SGBs for PTSD, including proposed mechanisms of action, clinical efficacy across diverse patient populations, safety profile, and potential avenues for further exploration and refinement. By synthesizing the latest evidence and insights, this review aims to provide clinicians and researchers with a comprehensive understanding of the role of SGBs in PTSD management, ultimately informing clinical practice and guiding future research endeavors in this area of mental health intervention.

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