Fourth-generation Epidermal Growth Factor Receptor-tyrosine Kinases Inhibitors: Hope and Challenges
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References
1.
Lu X, Zhang T, Zhu S, Xun Q, Tong L, Hu X
. Discovery of JND3229 as a New EGFR Mutant Inhibitor with In Vivo Monodrug Efficacy. ACS Med Chem Lett. 2018; 9(11):1123-1127.
PMC: 6231186.
DOI: 10.1021/acsmedchemlett.8b00373.
View
2.
To C, Jang J, Chen T, Park E, Mushajiang M, De Clercq D
. Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor. Cancer Discov. 2019; 9(7):926-943.
PMC: 6664433.
DOI: 10.1158/2159-8290.CD-18-0903.
View
3.
Engelhardt H, Bose D, Petronczki M, Scharn D, Bader G, Baum A
. Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors. J Med Chem. 2019; 62(22):10272-10293.
DOI: 10.1021/acs.jmedchem.9b01169.
View
4.
Lu X, Yu L, Zhang Z, Ren X, Smaill J, Ding K
. Targeting EGFR and EGFR resistance mutations in NSCLC: Current developments in medicinal chemistry. Med Res Rev. 2018; 38(5):1550-1581.
DOI: 10.1002/med.21488.
View
5.
Lee D
. Treatments for EGFR-mutant non-small cell lung cancer (NSCLC): The road to a success, paved with failures. Pharmacol Ther. 2017; 174:1-21.
DOI: 10.1016/j.pharmthera.2017.02.001.
View