Diagnosis and Management of Eosinophilic Esophagitis and Esophageal Food Impaction in Adults : A position Paper Issued by the Austrian Society of Gastroenterology and Hepatology (ÖGGH)

Overview

Journal Wien Klin Wochenschr

Publisher Springer

Specialty General Medicine

Date 2024 Sep 4

PMID 39230674

Authors

Hansjorg Schlager

Franziska Baumann-Durchschein

Karin Steidl

Michael Hafner

Patrick Dinkhauser

Michael Weitersberger

Josef Holzinger

Markus Mader

Hans Peter Grochenig

Christian Madl

Philipp Schreiner

Affiliations

Soon will be listed here.

Abstract

This position paper deals with an expert consensus on diagnosis and management of eosinophilic esophagitis and esophageal food impaction issued by the Austrian Eosinophilic Esophagitis Network, a working group under the patronage of the Austrian Society of Gastroenterology and Hepatology (ÖGGH). In need of a standardized approach on the management of EoE, recommendations were made based on international guidelines and landmark studies.

References

Ma C, Schoepfer A, Safroneeva E . Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS): An International Multidisciplinary Consensus. Gastroenterology. 2021; 161(3):748-755. DOI: 10.1053/j.gastro.2021.04.080. View

Hamant L, Freeman C, Garg S, Wright B, Schroeder S . Eosinophilic esophagitis may persist after discontinuation of oral immunotherapy. Ann Allergy Asthma Immunol. 2020; 126(3):299-302. PMC: 7897277. DOI: 10.1016/j.anai.2020.12.007. View

Miehlke S, Hruz P, Vieth M, Bussmann C, von Arnim U, Bajbouj M . A randomised, double-blind trial comparing budesonide formulations and dosages for short-term treatment of eosinophilic oesophagitis. Gut. 2015; 65(3):390-9. PMC: 4789829. DOI: 10.1136/gutjnl-2014-308815. View

Vermeulen B, de Zwart M, Sijben J, Soons E, van der Weerd L, Arese D . Risk factors and clinical outcomes of endoscopic dilation in benign esophageal strictures: a long-term follow-up study. Gastrointest Endosc. 2020; 91(5):1058-1066. DOI: 10.1016/j.gie.2019.12.040. View

Lin T, Wang C, Wang F, Kang E, Hwang Y . Association between Dupilumab and Conjunctivitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pharmaceutics. 2023; 15(4). PMC: 10145140. DOI: 10.3390/pharmaceutics15041031. View

Straumann A, Conus S, Degen L, Frei C, Bussmann C, Beglinger C . Long-term budesonide maintenance treatment is partially effective for patients with eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2011; 9(5):400-9.e1. DOI: 10.1016/j.cgh.2011.01.017. View

Nielsen J, Lager D, Lewin M, Rendon G, Roberts C . The optimal number of biopsy fragments to establish a morphologic diagnosis of eosinophilic esophagitis. Am J Gastroenterol. 2014; 109(4):515-20. DOI: 10.1038/ajg.2013.463. View

Biedermann L, Holbreich M, Atkins D, Chehade M, Dellon E, Furuta G . Food-induced immediate response of the esophagus-A newly identified syndrome in patients with eosinophilic esophagitis. Allergy. 2020; 76(1):339-347. DOI: 10.1111/all.14495. View

Lucendo A, Miehlke S, Schlag C, Vieth M, von Arnim U, Molina-Infante J . Efficacy of Budesonide Orodispersible Tablets as Induction Therapy for Eosinophilic Esophagitis in a Randomized Placebo-Controlled Trial. Gastroenterology. 2019; 157(1):74-86.e15. DOI: 10.1053/j.gastro.2019.03.025. View

10.

Upparahalli Venkateshaiah S, Kandikattu H, Yadavalli C, Mishra A . Eosinophils and T cell surface molecule transcript levels in the blood differentiate eosinophilic esophagitis (EoE) from GERD. Int J Basic Clin Immunol. 2021; 4(1-2):1-8. PMC: 8457322. View

11.

Vieira M, Gugelmin E, Percicote A, Ribeiro M, de Miranda R, Vieira G . Intra- and interobserver agreement of histopathological findings in pediatric patients with eosinophilic esophagitis. J Pediatr (Rio J). 2021; 98(1):26-32. PMC: 9432003. DOI: 10.1016/j.jped.2021.03.004. View

12.

Krill T, Samuel R, Vela A, Marcondes F, Zaibaq J, Guturu P . Outcomes of delayed endoscopic management for esophageal soft food impactions. Gastrointest Endosc. 2019; 91(4):806-812. DOI: 10.1016/j.gie.2019.12.020. View

13.

Lee C, Dellon E . Real-World Efficacy of Dupilumab in Severe, Treatment-Refractory, and Fibrostenotic Patients With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2023; 22(2):252-258. DOI: 10.1016/j.cgh.2023.08.015. View

14.

Lucendo A, Molina-Infante J, Arias A, von Arnim U, Bredenoord A, Bussmann C . Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults. United European Gastroenterol J. 2017; 5(3):335-358. PMC: 5415218. DOI: 10.1177/2050640616689525. View

15.

Miehlke S . Clinical features of Eosinophilic esophagitis in children and adults. Best Pract Res Clin Gastroenterol. 2015; 29(5):739-748. DOI: 10.1016/j.bpg.2015.09.005. View

16.

Gonsalves N, Yang G, Doerfler B, Ritz S, Ditto A, Hirano I . Elimination diet effectively treats eosinophilic esophagitis in adults; food reintroduction identifies causative factors. Gastroenterology. 2012; 142(7):1451-9.e1. DOI: 10.1053/j.gastro.2012.03.001. View

17.

Leung J, Mehrzad R, Hundal N, Alejos A, Hesterberg P, Katz A . Longitudinal Perspective on Managing Refractory Eosinophilic Esophagitis. J Allergy Clin Immunol Pract. 2015; 3(6):951-6. PMC: 5045894. DOI: 10.1016/j.jaip.2015.06.024. View

18.

Underwood B, Troutman T, Schwartz J . Breaking down the complex pathophysiology of eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2022; 130(1):28-39. PMC: 10165615. DOI: 10.1016/j.anai.2022.10.026. View

19.

Molina-Infante J, Rivas M, Hernandez-Alonso M, Vinagre-Rodriguez G, Mateos-Rodriguez J, Duenas-Sadornil C . Proton pump inhibitor-responsive oesophageal eosinophilia correlates with downregulation of eotaxin-3 and Th2 cytokines overexpression. Aliment Pharmacol Ther. 2014; 40(8):955-65. DOI: 10.1111/apt.12914. View

20.

Doerfler B, Bryce P, Hirano I, Gonsalves N . Practical approach to implementing dietary therapy in adults with eosinophilic esophagitis: the Chicago experience. Dis Esophagus. 2014; 28(1):42-58. DOI: 10.1111/dote.12175. View