Detection of Benign Granular Cell Tumor of the Breast Via F-PSMA-PET/CT in a Patient with Very High-risk Prostate Cancer: A Case Report

Overview

Journal SAGE Open Med Case Rep

Publisher Sage Publications

Specialty General Medicine

Date 2024 Sep 3

PMID 39224763

Authors

Kamyar Ghabili

Rushi Rajyaguru

Alexandra De La Plante

Kristine L Widders

Alison L Chetlen

Angela I Choe

Claudia J Kasales

Affiliations

Soon will be listed here.

Abstract

Incidental extra-prostatic prostate-specific membrane antigen (PSMA) uptake on initial staging positron emission tomography/computed tomography (PET/CT) scans poses diagnostic challenges, as it can be associated with various benign and malignant lesions. We present the case of a 68-year-old man with very high-risk prostate cancer who was incidentally discovered to have a benign granular cell tumor in the breast initially detected on PSMA-PET/CT. Imaging studies and biopsy were pivotal in the diagnosis, as the tumor's appearance was concerning for breast carcinoma. Recognizing extra-prostatic PSMA uptake in the breast, particularly in patients with prostate cancer, is crucial for guiding appropriate management, accurately interpreting subsequent imaging findings, and assessing radiologic-pathologic correlation.

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