Bibliometric Analysis of Research on Osteoarthritis and Extracellular Vesicles: Trends and Frontiers

Overview

Journal Heliyon

Specialty Social Sciences

Date 2024 Sep 3

PMID 39224260

Authors

Yongkang Ding

Lu Liang

Ye Guo

Bing Zhu

Affiliations

Soon will be listed here.

Abstract

Extensive research has made significant progress in exploring the potential application of extracellular vesicles (EV) in the diagnosis and treatment of osteoarthritis (OA). However, there is current a lack of study on bibliometrics. In this study, we completed a novel bibliometric analysis of EV research in OA over the past two decades. Specifically, we identified a total of 354 relevant publications obtained between January 1, 2003 and December 31, 2022. We also provided a description of the distribution information regarding the countries or regions of publication, institutions involved, journals, authors, citations, and keywords. The primary research focuses encompassed the role of extracellular vesicles in the diagnosis of OA, delivery of active ingredients, treatment strategies, and cartilage repair. These findings highlight the latest research frontiers and emerging areas, providing valuable insights for further investigations on the application of extracellular vesicles in the context of osteoarthritis.

References

Wang Y, Bai J, Zhang L, Liu H, Wang W, Liu Z . Advances in studies on the plant rhizosphere microorganisms in wetlands: A visualization analysis based on CiteSpace. Chemosphere. 2023; 317:137860. DOI: 10.1016/j.chemosphere.2023.137860. View

Hao Y, Song H, Zhou Z, Chen X, Li H, Zhang Y . Promotion or inhibition of extracellular vesicle release: Emerging therapeutic opportunities. J Control Release. 2021; 340:136-148. DOI: 10.1016/j.jconrel.2021.10.019. View

Peng Y, Tang R, Xu Q, Mei S, Zhou Y, Feng J . Worldwide productivity and research trend of publications concerning extracellular vesicles role in fibrosis: A bibliometric study from 2013 to 2022. Heliyon. 2024; 10(2):e24357. PMC: 10826165. DOI: 10.1016/j.heliyon.2024.e24357. View

Wen P, Liu R, Wang J, Wang Y, Song W, Zhang Y . Bibliometric insights from publications on subchondral bone research in osteoarthritis. Front Physiol. 2023; 13:1095868. PMC: 9814489. DOI: 10.3389/fphys.2022.1095868. View

Zhang Z, Yang Y, Kong W, Huang S, Tan Y, Huang S . A Bibliometric and Visual Analysis of Single Nucleotide Polymorphism Studies in Depression. Curr Neuropharmacol. 2023; 22(2):302-322. PMC: 10788886. DOI: 10.2174/1570159X21666230815125430. View

Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K . Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986; 29(8):1039-49. DOI: 10.1002/art.1780290816. View

Maehara M, Toyoda E, Takahashi T, Watanabe M, Sato M . Potential of Exosomes for Diagnosis and Treatment of Joint Disease: Towards a Point-of-Care Therapy for Osteoarthritis of the Knee. Int J Mol Sci. 2021; 22(5). PMC: 7961842. DOI: 10.3390/ijms22052666. View

Matsuzaka Y, Yashiro R . Therapeutic Strategy of Mesenchymal-Stem-Cell-Derived Extracellular Vesicles as Regenerative Medicine. Int J Mol Sci. 2022; 23(12). PMC: 9224400. DOI: 10.3390/ijms23126480. View

Mortati L, de Girolamo L, Perucca Orfei C, Vigano M, Brayda-Bruno M, Ragni E . In Vitro Study of Extracellular Vesicles Migration in Cartilage-Derived Osteoarthritis Samples Using Real-Time Quantitative Multimodal Nonlinear Optics Imaging. Pharmaceutics. 2020; 12(8). PMC: 7464389. DOI: 10.3390/pharmaceutics12080734. View

10.

Zhang W, Li M, Li X, Wang X, Liu Y, Yang J . Global trends and research status in ankylosing spondylitis clinical trials: a bibliometric analysis of the last 20 years. Front Immunol. 2024; 14:1328439. PMC: 10823346. DOI: 10.3389/fimmu.2023.1328439. View

11.

Liu Z, Zhuang Y, Fang L, Yuan C, Wang X, Lin K . Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis. Bioact Mater. 2022; 22:423-452. PMC: 9588998. DOI: 10.1016/j.bioactmat.2022.10.012. View

12.

Anderson H, Mulhall D, Garimella R . Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis. Lab Invest. 2010; 90(11):1549-57. DOI: 10.1038/labinvest.2010.152. View

13.

Durieux V, Gevenois P . Bibliometric indicators: quality measurements of scientific publication. Radiology. 2010; 255(2):342-51. DOI: 10.1148/radiol.09090626. View

14.

Xu X, Liang Y, Li X, Ouyang K, Wang M, Cao T . Exosome-mediated delivery of kartogenin for chondrogenesis of synovial fluid-derived mesenchymal stem cells and cartilage regeneration. Biomaterials. 2020; 269:120539. DOI: 10.1016/j.biomaterials.2020.120539. View

15.

Jin Y, Xu M, Zhu H, Dong C, Ji J, Liu Y . Therapeutic effects of bone marrow mesenchymal stem cells-derived exosomes on osteoarthritis. J Cell Mol Med. 2021; 25(19):9281-9294. PMC: 8500984. DOI: 10.1111/jcmm.16860. View

16.

Jiang S, Liu Y, Zheng H, Zhang L, Zhao H, Sang X . Evolutionary patterns and research frontiers in neoadjuvant immunotherapy: a bibliometric analysis. Int J Surg. 2023; 109(9):2774-2783. PMC: 10498839. DOI: 10.1097/JS9.0000000000000492. View

17.

Matejova J, Fecskeova L, Slovinska L, Harvanova D, Spakova T, Bzdilova J . Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: a primary study of a novel and promising diagnostic tool of the disease. Sci Rep. 2023; 13(1):20071. PMC: 10654566. DOI: 10.1038/s41598-023-47074-z. View

18.

Glyn-Jones S, Palmer A, Agricola R, Price A, Vincent T, Weinans H . Osteoarthritis. Lancet. 2015; 386(9991):376-87. DOI: 10.1016/S0140-6736(14)60802-3. View

19.

Kato T, Miyaki S, Ishitobi H, Nakamura Y, Nakasa T, Lotz M . Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes. Arthritis Res Ther. 2014; 16(4):R163. PMC: 4261911. DOI: 10.1186/ar4679. View

20.

Wang Z, Yan K, Ge G, Zhang D, Bai J, Guo X . Exosomes derived from miR-155-5p-overexpressing synovial mesenchymal stem cells prevent osteoarthritis via enhancing proliferation and migration, attenuating apoptosis, and modulating extracellular matrix secretion in chondrocytes. Cell Biol Toxicol. 2020; 37(1):85-96. DOI: 10.1007/s10565-020-09559-9. View