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Metabolic Associated Fatty Liver Disease (MAFLD): Assessing the Knowledge and Practice of Primary Care Doctors in Seremban District, Negeri Sembilan

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Specialty Public Health
Date 2024 Sep 2
PMID 39220239
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Abstract

Introduction: Metabolic-associated fatty liver disease (MAFLD) is the liver manifestation of metabolic syndrome, which is commonly seen in primary care settings. This study aimed to determine the knowledge and practice of primary care physicians regarding MAFLD in Seremban District, Negeri Sembilan.

Methods: This cross-sectional study was conducted among medical officers in 14 health clinics in Seremban District, using a validated, self-administered online questionnaire.

Results: A total of 240 medical officers from 14 health clinics in Seremban District, participated in this study. Most participants (85.4%) passed the knowledge test. Their practice was acceptable, but only a minority were familiar with non-invasive testing of liver fibrosis (e.g. APRI or FIB-4), medication and specific diet for the treatment of MAFLD.

Conclusion: Most primary care physicians in Seremban District are knowledgeable in identifying risk factors and managing patients with MAFLD. However, there are still areas to improve in terms of management, particularly regarding the use of silymarin, vitamin E and pioglitazone.

References
1.
Ratziu V, Giral P, Jacqueminet S, Charlotte F, Hartemann-Heurtier A, Serfaty L . Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. Gastroenterology. 2008; 135(1):100-10. DOI: 10.1053/j.gastro.2008.03.078. View

2.
Duseja A, Chalasani N . Epidemiology and risk factors of nonalcoholic fatty liver disease (NAFLD). Hepatol Int. 2015; 7 Suppl 2:755-64. DOI: 10.1007/s12072-013-9480-x. View

3.
Younossi Z, Anstee Q, Marietti M, Hardy T, Henry L, Eslam M . Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention. Nat Rev Gastroenterol Hepatol. 2017; 15(1):11-20. DOI: 10.1038/nrgastro.2017.109. View

4.
Li B, Zhang C, Zhan Y . Nonalcoholic Fatty Liver Disease Cirrhosis: A Review of Its Epidemiology, Risk Factors, Clinical Presentation, Diagnosis, Management, and Prognosis. Can J Gastroenterol Hepatol. 2018; 2018:2784537. PMC: 6051295. DOI: 10.1155/2018/2784537. View

5.
Cohen-Schotanus J, van der Vleuten C . A standard setting method with the best performing students as point of reference: practical and affordable. Med Teach. 2010; 32(2):154-60. DOI: 10.3109/01421590903196979. View