The Reliability and Validity of Rapid Transcranial Magnetic Stimulation Mapping for Muscles Under Active Contraction

Overview

Journal BMC Neurosci

Publisher Biomed Central

Specialty Neurology

Date 2024 Aug 30

PMID 39215217

Authors

Nahian S Chowdhury

Wei-Ju Chang

Rocco Cavaleri

Alan K I Chiang

Siobhan M Schabrun

Affiliations

Soon will be listed here.

Abstract

Rapid mapping is a transcranial magnetic stimulation (TMS) mapping method which can significantly reduce data collection time compared to traditional approaches. However, its validity and reliability has only been established for upper-limb muscles during resting-state activity. Here, we determined the validity and reliability of rapid mapping for non-upper limb muscles that require active contraction during TMS: the masseter and quadriceps muscles. Eleven healthy participants attended two sessions, spaced two hours apart, each involving rapid and 'traditional' mapping of the masseter muscle and three quadriceps muscles (rectus femoris, vastus medialis, vastus lateralis). Map parameters included map volume, map area and centre of gravity (CoG) in the medial-lateral and anterior-posterior directions. Low to moderate measurement errors (%SEM = 10-32) were observed across muscles. Relative reliability varied from good-to-excellent (ICC = 0.63-0.99) for map volume, poor-to-excellent (ICC = 0.11-0.86) for map area, and fair-to-excellent for CoG (ICC = 0.25-0.8) across muscles. There was Bayesian evidence of equivalence (BF's > 3) in most map outcomes between rapid and traditional maps across all muscles, supporting the validity of the rapid mapping method. Overall, rapid TMS mapping produced similar estimates of map parameters to the traditional method, however the reliability results were mixed. As mapping of non-upper limb muscles is relatively challenging, rapid mapping is a promising substitute for traditional mapping, however further work is required to refine this method.

References

Tsao H, Danneels L, Hodges P . ISSLS prize winner: Smudging the motor brain in young adults with recurrent low back pain. Spine (Phila Pa 1976). 2011; 36(21):1721-7. DOI: 10.1097/BRS.0b013e31821c4267. View

Guggisberg A, Dubach P, Hess C, Wuthrich C, Mathis J . Motor evoked potentials from masseter muscle induced by transcranial magnetic stimulation of the pyramidal tract: the importance of coil orientation. Clin Neurophysiol. 2001; 112(12):2312-9. DOI: 10.1016/s1388-2457(01)00677-0. View

Chang W, Bennell K, Hodges P, Hinman R, Liston M, Schabrun S . Combined exercise and transcranial direct current stimulation intervention for knee osteoarthritis: protocol for a pilot randomised controlled trial. BMJ Open. 2015; 5(8):e008482. PMC: 4550738. DOI: 10.1136/bmjopen-2015-008482. View

Richter L, Neumann G, Oung S, Schweikard A, Trillenberg P . Optimal coil orientation for transcranial magnetic stimulation. PLoS One. 2013; 8(4):e60358. PMC: 3623976. DOI: 10.1371/journal.pone.0060358. View

Chowdhury N, Chang W, Millard S, Skippen P, Bilska K, Seminowicz D . The Effect of Acute and Sustained Pain on Corticomotor Excitability: A Systematic Review and Meta-Analysis of Group and Individual Level Data. J Pain. 2022; 23(10):1680-1696. DOI: 10.1016/j.jpain.2022.04.012. View

Dziak J, Dierker L, Abar B . The Interpretation of Statistical Power after the Data have been Gathered. Curr Psychol. 2020; 39(3):870-877. PMC: 7286546. DOI: 10.1007/s12144-018-0018-1. View

Atkinson G, Nevill A . Statistical methods for assessing measurement error (reliability) in variables relevant to sports medicine. Sports Med. 1998; 26(4):217-38. DOI: 10.2165/00007256-199826040-00002. View

Coqueiro K, Bevilaqua-Grossi D, Berzin F, Soares A, Candolo C, Monteiro-Pedro V . Analysis on the activation of the VMO and VLL muscles during semisquat exercises with and without hip adduction in individuals with patellofemoral pain syndrome. J Electromyogr Kinesiol. 2005; 15(6):596-603. DOI: 10.1016/j.jelekin.2005.03.001. View

Wilson S, Thickbroom G, Mastaglia F . Transcranial magnetic stimulation mapping of the motor cortex in normal subjects. The representation of two intrinsic hand muscles. J Neurol Sci. 1993; 118(2):134-44. DOI: 10.1016/0022-510x(93)90102-5. View

10.

Kleim J, Kleim E, Cramer S . Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Nat Protoc. 2007; 2(7):1675-84. DOI: 10.1038/nprot.2007.206. View

11.

van Doorn J, den Bergh D, Bohm U, Dablander F, Derks K, Draws T . The JASP guidelines for conducting and reporting a Bayesian analysis. Psychon Bull Rev. 2020; 28(3):813-826. PMC: 8219590. DOI: 10.3758/s13423-020-01798-5. View

12.

Bland J, Altman D . Statistical methods for assessing agreement between two methods of clinical measurement. Lancet. 1986; 1(8476):307-10. View

13.

Macaluso G, Pavesi G, Bonanini M, Mancia D, GENNARI P . Motor-evoked potentials in masseter muscle by electrical and magnetic stimulation in intact alert man. Arch Oral Biol. 1990; 35(8):623-8. DOI: 10.1016/0003-9969(90)90028-9. View

14.

Schwenkreis P, Pleger B, Cornelius B, Weyen U, Dertwinkel R, Zenz M . Reorganization in the ipsilateral motor cortex of patients with lower limb amputation. Neurosci Lett. 2003; 349(3):187-90. DOI: 10.1016/s0304-3940(03)00838-3. View

15.

Uy J, Ridding M, Miles T . Stability of maps of human motor cortex made with transcranial magnetic stimulation. Brain Topogr. 2002; 14(4):293-7. DOI: 10.1023/a:1015752711146. View

16.

Nazarova M, Novikov P, Ivanina E, Kozlova K, Dobrynina L, Nikulin V . Mapping of multiple muscles with transcranial magnetic stimulation: absolute and relative test-retest reliability. Hum Brain Mapp. 2021; 42(8):2508-2528. PMC: 8090785. DOI: 10.1002/hbm.25383. View

17.

Ludemann-Podubecka J, Nowak D . Mapping cortical hand motor representation using TMS: A method to assess brain plasticity and a surrogate marker for recovery of function after stroke?. Neurosci Biobehav Rev. 2016; 69:239-51. DOI: 10.1016/j.neubiorev.2016.07.006. View

18.

Temesi J, Ly S, Millet G . Reliability of single- and paired-pulse transcranial magnetic stimulation for the assessment of knee extensor muscle function. J Neurol Sci. 2017; 375:442-449. DOI: 10.1016/j.jns.2017.02.037. View

19.

Ngomo S, Leonard G, Moffet H, Mercier C . Comparison of transcranial magnetic stimulation measures obtained at rest and under active conditions and their reliability. J Neurosci Methods. 2012; 205(1):65-71. DOI: 10.1016/j.jneumeth.2011.12.012. View

20.

van de Ruit M, Perenboom M, Grey M . TMS brain mapping in less than two minutes. Brain Stimul. 2015; 8(2):231-9. DOI: 10.1016/j.brs.2014.10.020. View