Vaccination Coverage of People Living with HIV: Before and After Interventional Action

Overview

Journal Vaccines (Basel)

Date 2024 Aug 29

PMID 39204022

Authors

Larissa Gerin

Elucir Gir

Lis Aparecida de Souza Neves

Luzia Marcia Romanholi Passos

Renato de Avila Kfouri

Bruno Spire

Renata Karina Reis

Affiliations

Soon will be listed here.

Abstract

This is a quasi-experimental study that assessed PLHIV vaccination coverage before and after health professionals participated in a training course on PLHIV immunization. The vaccination coverage of 645 PLHIV was assessed in the pre-intervention phase. The vaccine with the best coverage was diphtheria and tetanus (82.64%) and the one with the lowest rate of adequately vaccinated was measles, mumps, and rubella (38.27%). Individuals aged between 30 and 39 years had a 74.00% (1-0.26) lower chance of having the full vaccination schedule when compared to those aged between 10 and 19 years, and among those over 40 years, the chance was 87.00% (1-0.13) lower. Those who were vaccinated in Specialized Care Services (SCS) were 5.77 times more likely to be adequately vaccinated when compared to those who were vaccinated in other health services. Regarding the entire vaccination schedule evaluated, the number of adequately vaccinated increased from 47 (7.29%) to 76 (11.78%). Interventions targeting health professionals were effective in increasing vaccination coverage among PLHIV; however, the achieved coverage remained below the desired level. It is necessary to act on health professionals' knowledge and other aspects to effectively increase vaccination coverage.

References

McClung N, Burnett J, Wejnert C, Markowitz L, Meites E . Human papillomavirus vaccination coverage among men who have sex with men-National HIV Behavioral Surveillance, United States, 2017. Vaccine. 2020; 38(47):7417-7421. DOI: 10.1016/j.vaccine.2020.08.040. View

Crum N, Ahmad A . Immunity against measles in people with HIV: the need for more research and surveillance. AIDS. 2022; 36(9):1305-1306. DOI: 10.1097/QAD.0000000000003254. View

Grace D, Gaspar M, Paquette R, Rosenes R, Burchell A, Grennan T . HIV-positive gay men's knowledge and perceptions of Human Papillomavirus (HPV) and HPV vaccination: A qualitative study. PLoS One. 2018; 13(11):e0207953. PMC: 6264470. DOI: 10.1371/journal.pone.0207953. View

Bertolini D, Costa L, van der Heijden I, Sato H, de Sousa Marques H . Immunogenicity of a meningococcal serogroup C conjugate vaccine in HIV-infected children, adolescents, and young adults. Vaccine. 2012; 30(37):5482-6. DOI: 10.1016/j.vaccine.2012.06.069. View

Gagneux-Brunon A, Fresard A, Lucht F, Botelho-Nevers E . Vaccine coverage in PLWH: disparities and potential impact of vaccine hesitancy. Hum Vaccin Immunother. 2018; 15(2):305-306. PMC: 6422464. DOI: 10.1080/21645515.2018.1534517. View

Crum-Cianflone N, Wallace M . Vaccination in HIV-infected adults. AIDS Patient Care STDS. 2014; 28(8):397-410. PMC: 4117268. DOI: 10.1089/apc.2014.0121. View

Drewes J, Langer P, Ebert J, Kleiber D, Gusy B . Sociodemographic, HIV-Related Characteristics, and Health Care Factors as Predictors of Self-Reported Vaccination Coverage in a Nationwide Sample of People Aging with HIV in Germany. Int J Environ Res Public Health. 2021; 18(9). PMC: 8125659. DOI: 10.3390/ijerph18094901. View

Burns C, Banks R, Wilson B, Carter R, Jump R, Perez F . A virtual clinic improves pneumococcal vaccination coverage among patients living with HIV at a Veterans Affairs Medical Center. AIDS Care. 2017; 30(2):146-149. PMC: 5846095. DOI: 10.1080/09540121.2017.1390542. View

Parmejani P, Picone C, Alves A, Sartori A, Ibrahim K . Facilitating access to pneumococcal vaccine for people living with HIV: an experience report. Rev Esc Enferm USP. 2023; 56:e20210563. PMC: 10081583. DOI: 10.1590/1980-220X-REEUSP-2021-0563en. View

10.

Ho Y, Enohata T, Lopes M, de Sousa Dos Santos S . Vaccination in Brazilian HIV-infected adults: a cross-sectional study. AIDS Patient Care STDS. 2007; 22(1):65-70. DOI: 10.1089/apc.2007.0059. View

11.

El Chaer F, El Sahly H . Vaccination in the Adult Patient Infected with HIV: A Review of Vaccine Efficacy and Immunogenicity. Am J Med. 2019; 132(4):437-446. DOI: 10.1016/j.amjmed.2018.12.011. View

12.

Valour F, Cotte L, Voirin N, Godinot M, Ader F, Ferry T . Vaccination coverage against hepatitis A and B viruses, Streptococcus pneumoniae, seasonal flu, and A(H1N1)2009 pandemic influenza in HIV-infected patients. Vaccine. 2014; 32(35):4558-4564. DOI: 10.1016/j.vaccine.2014.06.015. View

13.

Jilich D, Maly M, Fleischhans L, Kulirova V, Machala L . Cross-sectional study on vaccination coverage in newly diagnosed HIV-infected persons in the Czech Republic. Cent Eur J Public Health. 2019; 27(3):217-222. DOI: 10.21101/cejph.a5830. View

14.

Blackwell C . Knowledge of Vaccination Needs of HIV-Infected Men Who Have Sex with Men in a National Sample of "Gay Friendly" Health care Providers. Public Health Nurs. 2016; 33(5):403-11. DOI: 10.1111/phn.12250. View

15.

Fresard A, Gagneux-Brunon A, Lucht F, Botelho-Nevers E, Launay O . Immunization of HIV-infected adult patients - French recommendations. Hum Vaccin Immunother. 2016; 12(11):2729-2741. PMC: 5137523. DOI: 10.1080/21645515.2016.1207013. View

16.

Lefebvre M, Secher S, Bouchez S, Vandamme Y, Fialaire P, Leautez S . Measles seroprevalence in human immunodeficiency virus-infected adults born in the era of measles vaccination. AIDS. 2022; 36(9):1273-1278. DOI: 10.1097/QAD.0000000000003220. View

17.

Nichols J, Eppes S . Meningococcal Vaccination:: An Update on Meningococcal Vaccine Recommendations for the Primary Care Physician. Dela J Public Health. 2022; 8(1):76-78. PMC: 8982922. DOI: 10.32481/djph.2022.03.012. View

18.

Thornton A, Jose S, Bhagani S, Chadwick D, Dunn D, Gilson R . Hepatitis B, hepatitis C, and mortality among HIV-positive individuals. AIDS. 2017; 31(18):2525-2532. PMC: 5690308. DOI: 10.1097/QAD.0000000000001646. View

19.

Neto L, Vieira J, Ronchi N . Vaccination coverage in a cohort of HIV-infected patients receiving care at an AIDS outpatient clinic in Espírito Santo, Brazil. Braz J Infect Dis. 2017; 21(5):515-519. PMC: 9425473. DOI: 10.1016/j.bjid.2017.03.021. View

20.

Hernandez-Garcia I, Roman-Calderon F, Lopez-Mendoza H, Aibar-Remon C . [Impact of an intervention to improve the vaccination coverage against in hiv patients]. Rev Esp Salud Publica. 2019; 93. PMC: 11582787. View