Unveiling the Psychological Consequences of Illness Perception in Pediatric Multiple Sclerosis: A Parent-Child Study

Overview

Journal Children (Basel)

Specialty Health Services

Date 2024 Aug 29

PMID 39201863

Authors

Roy Aloni

Gaya Asher

Amichai Ben-Ari

Shay Menascu

Affiliations

Soon will be listed here.

Abstract

Background: Previous research has emphasized the significant role of illness perception in chronic diseases, including Multiple Sclerosis. Limited research has been conducted on exploring illness perception in Pediatric Onset Multiple Sclerosis (POMS), parental illness perception, and the impact of differences in their illness perceptions on the emotional well-being of the child.

Method: This study included 65 dyads of children aged 10-17 and their parents, divided into the following two groups: (I) 32 dyads of children with POMS and their parents; and (II) 33 dyads of healthy children and their parents.

Results: Overall, 73.1% and 43.8% of the children with POMS met the criteria for probable anxiety and depression, respectively, compared to 27.3% and 0% of the healthy children. Differences were found between the dimensions of illness perception in the POMS children and their parents, in the areas of consequences, personal control, identity, and control factors. Multinomial Logistic Regression indicated that differences in child-parent illness perception increased the likelihood of comorbid anxiety and depression by 37%.

Discussion: These findings underscore the importance of alignment between children with POMS and their parents in illness perception. Healthcare providers should prioritize interventions that address illness perceptions and be mindful of the potential impact on depression and anxiety comorbidity.

References

Chaney J, Gamwell K, Baraldi A, Ramsey R, Cushing C, Mullins A . Parent Perceptions of Illness Uncertainty and Child Depressive Symptoms in Juvenile Rheumatic Diseases: Examining Caregiver Demand and Parent Distress as Mediators. J Pediatr Psychol. 2016; 41(9):941-51. DOI: 10.1093/jpepsy/jsw004. View

Lee J, Chitnis T . Pediatric Multiple Sclerosis. Semin Neurol. 2016; 36(2):148-53. DOI: 10.1055/s-0036-1579738. View

Leventhal H, Phillips L, Burns E . The Common-Sense Model of Self-Regulation (CSM): a dynamic framework for understanding illness self-management. J Behav Med. 2016; 39(6):935-946. DOI: 10.1007/s10865-016-9782-2. View

Charvet L, Cersosimo B, Schwarz C, Belman A, Krupp L . Behavioral Symptoms in Pediatric Multiple Sclerosis: Relation to Fatigue and Cognitive Impairment. J Child Neurol. 2016; 31(8):1062-7. PMC: 4925200. DOI: 10.1177/0883073816636227. View

Tsivgoulis G, Triantafyllou N, Papageorgiou C, Evangelopoulos M, Kararizou E, Sfagos C . Associations of the Expanded Disability Status Scale with anxiety and depression in multiple sclerosis outpatients. Acta Neurol Scand. 2006; 115(1):67-72. DOI: 10.1111/j.1600-0404.2006.00736.x. View

Huppke B, Ellenberger D, Rosewich H, Friede T, Gartner J, Huppke P . Clinical presentation of pediatric multiple sclerosis before puberty. Eur J Neurol. 2013; 21(3):441-6. DOI: 10.1111/ene.12327. View

Dempster M, Howell D, McCorry N . Illness perceptions and coping in physical health conditions: A meta-analysis. J Psychosom Res. 2015; 79(6):506-13. DOI: 10.1016/j.jpsychores.2015.10.006. View

Hanna M, Strober L . Anxiety and depression in Multiple Sclerosis (MS): Antecedents, consequences, and differential impact on well-being and quality of life. Mult Scler Relat Disord. 2020; 44:102261. PMC: 7719086. DOI: 10.1016/j.msard.2020.102261. View

Giordano A, Granella F, Lugaresi A, Martinelli V, Trojano M, Confalonieri P . Anxiety and depression in multiple sclerosis patients around diagnosis. J Neurol Sci. 2011; 307(1-2):86-91. DOI: 10.1016/j.jns.2011.05.008. View

10.

Ziccardi S, Crescenzo F, Calabrese M . "What Is Hidden behind the Mask?" Facial Emotion Recognition at the Time of COVID-19 Pandemic in Cognitively Normal Multiple Sclerosis Patients. Diagnostics (Basel). 2022; 12(1). PMC: 8774334. DOI: 10.3390/diagnostics12010047. View

11.

Till C, Udler E, Ghassemi R, Narayanan S, Arnold D, Banwell B . Factors associated with emotional and behavioral outcomes in adolescents with multiple sclerosis. Mult Scler. 2012; 18(8):1170-80. DOI: 10.1177/1352458511433918. View

12.

Parrish J, Weinstock-Guttman B, Smerbeck A, Benedict R, Yeh E . Fatigue and depression in children with demyelinating disorders. J Child Neurol. 2012; 28(6):713-8. DOI: 10.1177/0883073812450750. View

13.

Janssens A, Buljevac D, van Doorn P, van der Meche F, Polman C, Passchier J . Prediction of anxiety and distress following diagnosis of multiple sclerosis: a two-year longitudinal study. Mult Scler. 2007; 12(6):794-801. DOI: 10.1177/1352458506070935. View

14.

Broadbent E, Wilkes C, Koschwanez H, Weinman J, Norton S, Petrie K . A systematic review and meta-analysis of the Brief Illness Perception Questionnaire. Psychol Health. 2015; 30(11):1361-85. DOI: 10.1080/08870446.2015.1070851. View

15.

Melton T, Croarkin P, Strawn J, McClintock S . Comorbid Anxiety and Depressive Symptoms in Children and Adolescents: A Systematic Review and Analysis. J Psychiatr Pract. 2016; 22(2):84-98. PMC: 6267783. DOI: 10.1097/PRA.0000000000000132. View

16.

Barin L, Salmen A, Disanto G, Babacic H, Calabrese P, Chan A . The disease burden of Multiple Sclerosis from the individual and population perspective: Which symptoms matter most?. Mult Scler Relat Disord. 2018; 25:112-121. DOI: 10.1016/j.msard.2018.07.013. View

17.

Thompson A, Banwell B, Barkhof F, Carroll W, Coetzee T, Comi G . Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol. 2017; 17(2):162-173. DOI: 10.1016/S1474-4422(17)30470-2. View

18.

Bassi M, Falautano M, Cilia S, Goretti B, Grobberio M, Pattini M . Illness Perception and Well-Being Among Persons with Multiple Sclerosis and Their Caregivers. J Clin Psychol Med Settings. 2015; 23(1):33-52. DOI: 10.1007/s10880-015-9425-8. View

19.

Amato M, Goretti B, Ghezzi A, Lori S, Zipoli V, Portaccio E . Cognitive and psychosocial features of childhood and juvenile MS. Neurology. 2008; 70(20):1891-7. DOI: 10.1212/01.wnl.0000312276.23177.fa. View

20.

Jopson N, Moss-Morris R . The role of illness severity and illness representations in adjusting to multiple sclerosis. J Psychosom Res. 2003; 54(6):503-11; discussion 513-4. DOI: 10.1016/s0022-3999(02)00455-5. View