Metabolic Pathways in Hydrocephalus: Profiling with Proteomics and Advanced Imaging

Overview

Journal Metabolites

Publisher MDPI

Date 2024 Aug 28

PMID 39195508

Authors

Laura May Davis

Misun Hwang

Affiliations

Soon will be listed here.

Abstract

Hemorrhagic hydrocephalus is a common pathology in neonates with high mortality and morbidity. Current imaging approaches fail to capture the mechanisms behind its pathogenesis. Here, we discuss the processes underlying this pathology, the metabolic dysfunction that occurs as a result, and the ways in which these metabolic changes inform novel methods of clinical imaging. The imaging advances described allow earlier detection of the cellular and metabolic changes, leading to better outcomes for affected neonates.

Citing Articles

Current Diagnostic, Counseling, and Treatment Options in Non-Severe and Severe Apparently Isolated Fetal Ventriculomegaly.

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PMID: 39767835 PMC: 11673042. DOI: 10.3390/biomedicines12122929.

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