Effect of Diabetes Mellitus on the Spectrum of Uropathogens and the Antimicrobial Resistance in Patients with Urinary Tract Infection

Overview

Journal Arch Razi Inst

Specialties Allergy & Immunology
General Medicine
Veterinary Medicine

Date 2024 Aug 28

PMID 39192946

Authors

S Shahsavari

M Bakht

H Sadeghi

S Rahimi

F Movahed

V Chegini

S Gholamzadeh Khoei

Affiliations

Soon will be listed here.

Abstract

Patients with diabetes mellitus frequently experience urinary tract infections (UTIs). In the present study, we looked at how glycemic control affects diabetic patients' rates of UTI, the causing pathogens, the presence of multi-drug-resistant (MDR) and extensively drug-resistant organisms, and the infections' relation to diabetes. Diabetes patients' midstream urine samples were included, after collecting and identifying the organisms, disc diffusion antibiotic sensitivity tests were conducted. The HbA1c was measured for all patients. A total of 500 diabetic patients provided urine samples for this study, and 189 (37.2%) of them had UTIs. Compared to 59 patients with managed glycemia, 130 individuals in the uncontrolled glycemic group experienced the most UTI cases. In both diabetic groups, females had a significantly higher prevalence of UTI than males (88.4% and 11.6%, respectively). The most common bacterial isolate, , displayed 58.4% MDR. Regardless of age or gender, glycemic control in diabetes patients is essential for decreasing UTI rates.

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