Sero Epidemiological Study on Bovine Babesiosis in Cattle and Buffaloes in Sharkia Governorate, Egypt

Overview

Journal Open Vet J

Specialty Veterinary Medicine

Date 2024 Aug 23

PMID 39175968

Authors

Sarah Gamal Yousef

Nader Maher Sobhy

Heba Gouda

Mahmoud Helmy Emam

Affiliations

Soon will be listed here.

Abstract

Background: Bovine babesiosis represents a serious challenge for animal health, herd production, and profitability. Understanding the epidemiology and risk factors associated with babesiosis is critical to reduce their negative impacts.

Aim: Investigation of the seroprevalence and risk factors associated with () and () in five districts in Sharkia governorate using ELISA.

Methods: Across-sectional research was conducted to determine the seropositivity of babesiosis by collecting a total of 352 blood samples from 250 cattle and 102 buffaloes. A multivariate logistic regression model was implemented to evaluate the strength of the risk factors associated with both Babesia species infection.

Results: The seroprevalence of and was 42.6% and 17.0 %, respectively. The prevalence of babesiosis in cattle was found to be 48.8% for and 16.8% for . Inclusive, in buffaloes, the prevalence was 27.5% for and 17.6% for . Adult animals were more vulnerable to infection with babesia than young animals by 3-5 times, respectively. Males were more susceptible to and than females by 3.7 and 3.5 times. Similarly, the odds of infection in infested animals with ticks were 2-4 times higher than in animals without ticks.

Conclusion: The obtained results revealed that age, sex of the animal, and tick infestation were major risk factors for the seropositivity of both Babesia species. Inclusive, there was no evidence to support the premise that seroprevalence of babesiosis is correlated with the season and species.

References

Sharma A, Singla L, Tuli A, Kaur P, Batth B, Javed M . Molecular prevalence of Babesia bigemina and Trypanosoma evansi in dairy animals from Punjab, India, by duplex PCR: a step forward to the detection and management of concurrent latent infections. Biomed Res Int. 2013; 2013:893862. PMC: 3773408. DOI: 10.1155/2013/893862. View

Ibrahim H, Galon E, Tumwebaze M, Byamukama B, Liu M, Mohammed-Geba K . Serological Survey of Babesia bigemina and Babesia bovis in Cattle and Water Buffaloes from Menoufia Province, Egypt. Acta Parasitol. 2021; 66(4):1458-1465. DOI: 10.1007/s11686-021-00338-y. View

Fereig R, Mohamed S, Mahmoud H, AbouLaila M, Guswanto A, Nguyen T . Seroprevalence of Babesia bovis, B. bigemina, Trypanosoma evansi, and Anaplasma marginale antibodies in cattle in southern Egypt. Ticks Tick Borne Dis. 2016; 8(1):125-131. DOI: 10.1016/j.ttbdis.2016.10.008. View

Terkawi M, Huyen N, Shinuo C, Inpankaew T, Maklon K, AbouLaila M . Molecular and serological prevalence of Babesia bovis and Babesia bigemina in water buffaloes in the northeast region of Thailand. Vet Parasitol. 2011; 178(3-4):201-7. DOI: 10.1016/j.vetpar.2011.01.041. View

Mahmoud H, Rady A, Tanaka T . Molecular detection and characterization of and infecting cattle and buffalo in southern Egypt. Parasite Epidemiol Control. 2024; 25:e00340. PMC: 10847785. DOI: 10.1016/j.parepi.2024.e00340. View

Wesonga F, Gachohi J, Kitala P, Gathuma J, Njenga M . Seroprevalence of Anaplasma marginale and Babesia bigemina infections and associated risk factors in Machakos County, Kenya. Trop Anim Health Prod. 2016; 49(2):265-272. DOI: 10.1007/s11250-016-1187-2. View

Guswanto A, Allamanda P, Mariamah E, Sodirun S, Wibowo P, Indrayani L . Molecular and serological detection of bovine babesiosis in Indonesia. Parasit Vectors. 2017; 10(1):550. PMC: 5674684. DOI: 10.1186/s13071-017-2502-0. View

Rizk M, Salama A, El-Sayed S, Elsify A, El-Ashkar M, Ibrahim H . Animal level risk factors associated with Babesia and Theileria infections in cattle in Egypt. Acta Parasitol. 2017; 62(4):796-804. DOI: 10.1515/ap-2017-0096. View

Abas O, Abd-Elrahman A, Saleh A, Bessat M . Prevalence of tick-borne haemoparasites and their perceived co-occurrences with viral outbreaks of FMD and LSD and their associated factors. Heliyon. 2021; 7(3):e06479. PMC: 7980057. DOI: 10.1016/j.heliyon.2021.e06479. View

10.

Adham F, Abd-el-Samie E, Gabre R, el-Hussein H . Detection of tick blood parasites in Egypt using PCR assay I--Babesia bovis and Babesia bigemina. Parasitol Res. 2009; 105(3):721-30. DOI: 10.1007/s00436-009-1443-8. View

11.

Jacob S, Sengupta P, Paramanandham K, Suresh K, Chamuah J, Rudramurthy G . Bovine babesiosis: An insight into the global perspective on the disease distribution by systematic review and meta-analysis. Vet Parasitol. 2020; 283:109136. DOI: 10.1016/j.vetpar.2020.109136. View

12.

Ibrahim H, Adjou Moumouni P, Mohammed-Geba K, Sheir S, Hashem I, Cao S . Molecular and serological prevalence of Babesia bigemina and Babesia bovis in cattle and water buffalos under small-scale dairy farming in Beheira and Faiyum Provinces, Egypt. Vet Parasitol. 2013; 198(1-2):187-92. DOI: 10.1016/j.vetpar.2013.08.028. View

13.

Li Y, Luo Y, Cao S, Terkawi M, Lan D, Long P . Molecular and seroepidemiological survey of Babesia bovis and Babesia bigemina infections in cattle and water buffaloes in the central region of Vietnam. Trop Biomed. 2014; 31(3):406-13. View

14.

Bock R, Jackson L, de Vos A, Jorgensen W . Babesiosis of cattle. Parasitology. 2005; 129 Suppl:S247-69. DOI: 10.1017/s0031182004005190. View

15.

Criado-Fornelio A . A review of nucleic-acid-based diagnostic tests for Babesia and Theileria, with emphasis on bovine piroplasms. Parassitologia. 2007; 49 Suppl 1:39-44. View

16.

Jaimes-Duenez J, Triana-Chavez O, Mejia-Jaramillo A . Parasitological and molecular surveys reveal high rates of infection with vector-borne pathogens and clinical anemia signs associated with infection in cattle from two important livestock areas in Colombia. Ticks Tick Borne Dis. 2016; 8(2):290-299. DOI: 10.1016/j.ttbdis.2016.12.002. View

17.

Fakhar M, Hajihasani A, Maroufi S, Alizadeh H, Shirzad H, Piri F . An epidemiological survey on bovine and ovine babesiosis in Kurdistan Province, western Iran. Trop Anim Health Prod. 2011; 44(2):319-22. DOI: 10.1007/s11250-011-0023-y. View

18.

Mahmoud M, Kandil O, Nasr S, Hendawy S, Habeeb S, Mabrouk D . Serological and molecular diagnostic surveys combined with examining hematological profiles suggests increased levels of infection and hematological response of cattle to babesiosis infections compared to native buffaloes in Egypt. Parasit Vectors. 2015; 8:319. PMC: 4467044. DOI: 10.1186/s13071-015-0928-9. View

19.

Goes T, Goes V, Ribeiro M, Gontijo C . Bovine babesiosis: anti-erythrocyte antibodies purification from the sera of naturally infected cattle. Vet Immunol Immunopathol. 2007; 116(3-4):215-8. DOI: 10.1016/j.vetimm.2006.12.011. View