» Articles » PMID: 39174810

A Case of Adnexal Cutaneous Leishmaniasis in Washington DC

Overview
Publisher Springer
Specialty Ophthalmology
Date 2024 Aug 22
PMID 39174810
Authors
Affiliations
Soon will be listed here.
Abstract

Purpose: To report a rare non-endemic case of Leishmania aethiopica in Washington DC.

Case Report: A 68-year-old female presented for a routine examination with a complaint of right upper eyelid lesions for the past 5 months. On examination, a cluster of elevated and erythematous lesions extending from the medial canthus to the brow area of the right eye were seen. Initial treatment with Valtrex based on a suspected viral etiology failed. Although a biopsy was recommended at this time, the patient declined, and subsequent workup included nasolacrimal duct irrigation, blood work to rule out autoimmune etiology, a course of doxycycline, and an MRI, which yielded no improvement. Upon progression of the lesions into persistent plaques on the eyelids, a punch biopsy was performed, confirming leishmaniasis. The patient was then started on a 28-day course of oral miltefosine which led to complete resolution of her symptoms.

Conclusion: This case underlines the importance of a broad differential including non-endemic diseases, particularly in urban areas with frequent patient travel. Furthermore, the delayed punch biopsy in this case highlights the importance of patient counseling to ensure prompt diagnosis and treatment.

References
1.
Cohen J . Clinical practice: Herpes zoster. N Engl J Med. 2013; 369(3):255-63. PMC: 4789101. DOI: 10.1056/NEJMcp1302674. View

2.
van Henten S, Adriaensen W, Fikre H, Akuffo H, Diro E, Hailu A . Cutaneous Leishmaniasis Due to . EClinicalMedicine. 2019; 6:69-81. PMC: 6537575. DOI: 10.1016/j.eclinm.2018.12.009. View

3.
Satici A, Gurler B, Aslan G, Ozturk I . Ocular involvement in cutaneous leishmaniasis four cases with blepharoconjunctivitis. Eur J Epidemiol. 2004; 19(3):263-6. DOI: 10.1023/b:ejep.0000020346.15800.d3. View

4.
Sadeghian G, Nilfroushzadeh M, Moradi S, Hanjani S . Ocular leishmaniasis: a case report. Dermatol Online J. 2005; 11(2):19. View

5.
Jafari A, Akhyani M, Valikhani M, Ghodsi Z, Barikbin B, Toosi S . Bilateral cutaneous leishmaniasis of upper eyelids: a case report. Dermatol Online J. 2006; 12(1):20. View