Global Research Trends and Hotspots in Overweight/obese Comorbid with Depression Among Children and Adolescents: A Bibliometric Analysis

Overview

Journal World J Psychiatry

Publisher Baishideng Publishing Group

Specialty Psychiatry

Date 2024 Aug 21

PMID 39165557

Authors

Ya-Qi Wang

Tao-Tao Wu

Yan Li

Shi-En Cui

Ying-Shuai Li

Affiliations

Soon will be listed here.

Abstract

Background: Overweight/obesity combined with depression among children and adolescents (ODCA) is a global concern. The bidirectional relationship between depression and overweight/obesity often leads to their comorbidity. Childhood and adolescence represent critical periods for physical and psychological development, during which the comorbidity of overweight/obesity and depression may increase the risk of adverse health outcomes.

Aim: To evaluate the relationship between ODCA, we conduct a bibliometric analysis to aid in formulating prevention and treatment strategies.

Methods: From 2004 to 2023, articles related to ODCA were selected using the Science Citation Index Expanded from the Web of Science Core Collection. Bibliometric analysis of relevant publications, including countries/regions, institutions, authors, journals, references, and keywords, was conducted using the online bibliometric analysis platforms, CiteSpace, VOSviewer, and bibliometrix.

Results: Between 2004 and 2023, a total of 1573 articles were published on ODCA. The United States has made leading contributions in this field, with Harvard University emerging as the leading contributor in terms of research output, and Tanofsky being the most prolific author. The has shown significant activity in this domain. Based on the results of the keyword and reference analyses, inequality, adverse childhood experiences, and comorbidities have become hot topics in ODCA. Moreover, the impact of balanced-related behavior and exploration of the biological mechanisms, including the potential role of key adipocytokines and lipokines, as well as inflammation in ODCA, have emerged as frontier topics.

Conclusion: The trend of a significant increase in ODCA publications is expected to continue. The research findings will contribute to elucidating the pathogenic mechanisms of ODCA and its prevention and treatment.

Citing Articles

Gut-brain axis as a bridge in obesity and depression: Mechanistic exploration and therapeutic prospects.

Fang R, Pan X, Zeng X, Li Z, Chen B, Zeng H World J Psychiatry. 2025; 15(1):101134.

PMID: 39831021 PMC: 11684226. DOI: 10.5498/wjp.v15.i1.101134.

References

Doan T, Hutton D, Wright D, Prosser L . Estimating Transition Probabilities for Modeling Major Depression in Adolescents by Sex and Race or Ethnicity Combinations in the USA. Appl Health Econ Health Policy. 2024; 22(3):375-390. DOI: 10.1007/s40258-024-00872-6. View

Chen Q, Sun T, He Q, Yu J, Zhang X, Han L . Study of decreased serum levels of C1q/TNF-related protein 4 (CTRP4) in major depressive disorder. J Psychiatr Res. 2024; 172:274-280. DOI: 10.1016/j.jpsychires.2024.01.046. View

Jaeger V, Koletzko B, Luque V, Ferre N, Gruszfeld D, Gradowska K . Distribution of energy and macronutrient intakes across eating occasions in European children from 3 to 8 years of age: The EU Childhood Obesity Project Study. Eur J Nutr. 2022; 62(1):165-174. PMC: 9899743. DOI: 10.1007/s00394-022-02944-6. View

Sun P, Wang S, Hu Z . Three Problems in Meta-analysis of Prevalence of Obesity in European Children. JAMA Pediatr. 2020; 174(4):389. DOI: 10.1001/jamapediatrics.2019.5872. View

Ogden C, Fryar C, Hales C, Carroll M, Aoki Y, Freedman D . Differences in Obesity Prevalence by Demographics and Urbanization in US Children and Adolescents, 2013-2016. JAMA. 2018; 319(23):2410-2418. PMC: 6393914. DOI: 10.1001/jama.2018.5158. View

Majmudar D, East P, Martinez S, Blanco E, Lozoff B, Burrows R . Associations between adverse home environments and appetite hormones, adipokines, and adiposity among Chilean adolescents. Clin Obes. 2021; 12(1):e12488. DOI: 10.1111/cob.12488. View

Li J, Hall M, Shalev I, Schreier H, Gonzalez Zarzar T, Marcovici I . Hypothalamic-pituitary-adrenal axis attenuation and obesity risk in sexually abused females. Psychoneuroendocrinology. 2021; 129:105254. PMC: 8217375. DOI: 10.1016/j.psyneuen.2021.105254. View

Luppino F, de Wit L, Bouvy P, Stijnen T, Cuijpers P, Penninx B . Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch Gen Psychiatry. 2010; 67(3):220-9. DOI: 10.1001/archgenpsychiatry.2010.2. View

Matvienko-Sikar K, Butler E, Keeffe L, Dijk W, Hayes C, Huizink A . Prenatal maternal cortisol, stress and anxiety, and childhood obesity at 5 years: a nested case-control study. J Reprod Infant Psychol. 2023; :1-15. DOI: 10.1080/02646838.2023.2288298. View

10.

Korczak D, Cleverley K, Birken C, Pignatiello T, Mahmud F, McCrindle B . Cardiovascular Disease Risk Factors Among Children and Adolescents With Depression. Front Psychiatry. 2021; 12:702737. PMC: 8418089. DOI: 10.3389/fpsyt.2021.702737. View

11.

Honaker S, Simon S, Byars K, Simmons D, Williamson A, Meltzer L . Advancing Patient-Centered Care: An International Survey of Adolescent Perspectives on Insomnia. Behav Sleep Med. 2024; 22(5):571-592. PMC: 11365813. DOI: 10.1080/15402002.2024.2322519. View

12.

Kumari R, Nath B, Singh Y, Mallick R . Health-related physical fitness, physical activity and its correlates among school going adolescents in hilly state in north India: a cross sectional survey. BMC Public Health. 2024; 24(1):401. PMC: 10848408. DOI: 10.1186/s12889-024-17808-3. View

13.

Kyler K, Houtrow A, Hall M . Prevalence and Severity of Chronic Conditions Among Adolescents With Obesity. Child Obes. 2023; 20(1):68-71. DOI: 10.1089/chi.2022.0217. View

14.

Guerrini Usubini A, Bottacchi M, Bondesan A, Marazzi N, Castelnuovo G, Sartorio A . Behavioral and Emotional Problems in Children and Adolescents with Obesity: A Preliminary Report. J Clin Med. 2024; 13(2). PMC: 10816115. DOI: 10.3390/jcm13020459. View

15.

Franklin B, Jones A, Love D, Puckett S, Macklin J, White-Means S . Exploring mediators of food insecurity and obesity: a review of recent literature. J Community Health. 2011; 37(1):253-64. PMC: 3334290. DOI: 10.1007/s10900-011-9420-4. View

16.

. Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024; 403(10431):1027-1050. PMC: 7615769. DOI: 10.1016/S0140-6736(23)02750-2. View

17.

Lahlou N, Issad T, LeBouc Y, Carel J, Camoin L, Roger M . Mutations in the human leptin and leptin receptor genes as models of serum leptin receptor regulation. Diabetes. 2002; 51(6):1980-5. DOI: 10.2337/diabetes.51.6.1980. View

18.

Zhang X, Liu J, Ni Y, Yi C, Fang Y, Ning Q . Global Prevalence of Overweight and Obesity in Children and Adolescents: A Systematic Review and Meta-Analysis. JAMA Pediatr. 2024; 178(8):800-813. PMC: 11165417. DOI: 10.1001/jamapediatrics.2024.1576. View

19.

Martinez M, Damme K, Vargas T, Yang B, Rompilla D, Stephens J . Longitudinal study of peer victimization, social support, and mental health during early adolescence. Psychol Med. 2024; 54(9):1940-1955. PMC: 11298578. DOI: 10.1017/S0033291724000035. View

20.

Swaab D, Bao A, Lucassen P . The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev. 2005; 4(2):141-94. DOI: 10.1016/j.arr.2005.03.003. View