Patient, Family, and Community Factors Associated with Medication Adherence Among People with Hypertension or Diabetes: A Cross-sectional Analysis

Overview

Journal Explor Res Clin Soc Pharm

Date 2024 Aug 19

PMID 39157069

Authors

You Wu

Shangzhi Xiong

Gangjiao Zhu

Xinyue Chen

Mingyang Zhang

Enying Gong

Chong Li

Peng Jia

Truls Ostbye

Lijing L Yan

Affiliations

Soon will be listed here.

Abstract

Background: While suboptimal medication adherence remains an obstacle to the management of hypertension and diabetes in China, few studies have investigated associated factors with medication adherence on different dimensions simultaneously.

Objective: To systematically examine associated patient, family, and community factors with suboptimal medication adherence among people with hypertension and/or type 2 diabetes in China.

Methods: The study stratified a random sample of 622 adults aged 45 years or older with hypertension and/or type 2 diabetes from three southeast cities in China in 2019. Trained interviewers used the Morisky Green Levine Medication Adherence Scale, Self-Efficacy to Manage Chronic Disease (SEMCD) Scale, and the Family Adaptability, Partnership, Growth, Affection, and Resolve (APGAR) Scale to assess medication adherence, self-efficacy, and family function, respectively. Participants also reported their perceived satisfaction with community health services (quantity, quality, affordability, and overall acceptance). The study used the multivariable logistic regression to assess the association of patient, family, and community factors with suboptimal medication adherence.

Results: Among the participants, 42.9% reported suboptimal medication adherence. In the multivariable logistic regression model, male participants (odds ratio [OR] = 0.55, = 0.001) had higher medication adherence compared to females. Having a self-efficacy score that was lower than or equal to the sample mean was significantly associated with lower adherence (OR = 1.44, = 0.039). Participants unsatisfied with the affordability of community health services and medicine had lower adherence (OR = 2.18, 0.028) than those neutral or satisfied. There were no significant associations between family function and medication adherence.

Conclusions: Sex, self-efficacy, and perceived affordability of community health services were important factors associated with medication adherence. Healthcare professionals are recommended to consider multiple factors and leverage services and resources in community health centers when promoting medication adherence.

Citing Articles

Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis.

Tong X, Zou H, Zhang L, Chen W BMC Public Health. 2025; 25(1):404.

PMID: 39891108 PMC: 11786533. DOI: 10.1186/s12889-025-21656-0.

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