New Perspectives in the Treatment of Inflammatory Myofibroblastic Tumor with ALK Translocation: Case Report

Overview

Journal Case Rep Oncol

Publisher Karger

Specialty Oncology

Date 2024 Aug 15

PMID 39144250

Authors

Johana Benedetti Pedroza

Irene Carrasco Garcia

Gala Martinez Bernal

Isabel Miras Rodriguez

Affiliations

Soon will be listed here.

Abstract

Introduction: Inflammatory myofibroblastic tumor (IMT) is a rare entity, classified within soft tissue sarcomas. It is an intermediate malignancy tumor, which seldom presents as metastatic disease. The treatment of choice is surgery, except in cases where surgery is not possible due to localization or if it presents with metastatic disease. Approximately 50% of IMTs will exhibit ALK translocation, providing a therapeutic target for these patients.

Case Presentation: A case is presented of a patient with metastatic IMT in complete response to treatment with alectinib, maintained for over 4 years.

Conclusion: This case showed a long time complete response in patient with IMT treated with alectinib.

Citing Articles

Spontaneous Regression of an Inflammatory Myofibroblastic Tumor: A Case Report and a Review of the Literature.

Medici B, Caffari E, Salati M, Spallanzani A, Garajova I, Piacentini F Case Rep Oncol. 2024; 17(1):1208-1213.

PMID: 39474532 PMC: 11521496. DOI: 10.1159/000541337.

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