Recent Advances in Nanostructured Delivery Systems for Vancomycin

Overview

Journal Nanomedicine (Lond)

Specialty Biotechnology

Date 2024 Aug 15

PMID 39143926

Authors

Mohabbat Ansari

Mohsen Shahlaei

Simzar Hosseinzadeh

Sajad Moradi

Affiliations

Soon will be listed here.

Abstract

Despite the development of new generations of antibiotics, vancomycin remained as a high-efficacy antibiotic for treating the infections caused by MRSA. Researchers have explored various nanoformulations, aiming to enhance the therapeutic efficacy of vancomycin. Such novel formulations improve the effectiveness of drug cargoes in treating bacterial infections and minimizing the risk of adverse effects. The vast of researches have focuses on enhancing the permeation ability of vancomycin through different biological barriers especially those of gastrointestinal tract. Increasing the drug loading and tuning the drug release from nanocarrier are other important goal for many conducted studies. This study reviews the newest nano-based formulations for vancomycin as a key antibiotic in treating hospitalized bacterial infections.

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