Transforming Healthcare with Nanomedicine: A SWOT Analysis of Drug Delivery Innovation

Overview

Journal Drug Des Devel Ther

Specialty Pharmacology

Date 2024 Aug 12

PMID 39132625

Authors

Hao Zhang

Suping Li

Xingming Ma

Affiliations

Soon will be listed here.

Abstract

Objective: Nanomedicine represents a transformative approach in biomedical applications. This study aims to delineate the application of nanomedicine in the biomedical field through the strengths, weaknesses, opportunities, and threats (SWOT) analysis to evaluate its efficacy and potential in clinical applications.

Methods: The SWOT analysis framework was employed to systematically review and assess the internal strengths and weaknesses, along with external opportunities and threats of nanomedicine. This method provides a balanced consideration of the potential benefits and challenges.

Results: Findings from the SWOT analysis indicate that nanomedicine presents significant potential in drug delivery, diagnostic imaging, and tissue engineering. Nonetheless, it faces substantial hurdles such as safety issues, environmental concerns, and high development costs. Critical areas for development were identified, particularly concerning its therapeutic potential and the uncertainties surrounding long-term effects.

Conclusion: Nanomedicine holds substantial promise in driving medical innovation. However, successful clinical translation requires addressing safety, cost, and regulatory challenges. Interdisciplinary collaboration and comprehensive strategic planning are crucial for the safe and effective application of nanomedicine.

Citing Articles

Transforming Medicine: Cutting-Edge Applications of Nanoscale Materials in Drug Delivery.

Tenchov R, Hughes K, Ganesan M, Iyer K, Ralhan K, Lotti Diaz L ACS Nano. 2025; 19(4):4011-4038.

PMID: 39823199 PMC: 11803921. DOI: 10.1021/acsnano.4c09566.

References

Tang L, Fan T, Borst L, Cheng J . Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates. ACS Nano. 2012; 6(5):3954-66. PMC: 3555148. DOI: 10.1021/nn300149c. View

Boulaiz H, Alvarez P, Ramirez A, Marchal J, Prados J, Rodriguez-Serrano F . Nanomedicine: application areas and development prospects. Int J Mol Sci. 2011; 12(5):3303-21. PMC: 3116192. DOI: 10.3390/ijms12053303. View

de Jong W, Borm P . Drug delivery and nanoparticles:applications and hazards. Int J Nanomedicine. 2008; 3(2):133-49. PMC: 2527668. DOI: 10.2147/ijn.s596. View

Di J, Gao X, Du Y, Zhang H, Gao J, Zheng A . Size, shape, charge and "stealthy" surface: Carrier properties affect the drug circulation time . Asian J Pharm Sci. 2021; 16(4):444-458. PMC: 8520042. DOI: 10.1016/j.ajps.2020.07.005. View

Lu Y, Lv Y, Li T . Hybrid drug nanocrystals. Adv Drug Deliv Rev. 2019; 143:115-133. DOI: 10.1016/j.addr.2019.06.006. View

Schlichte L, Setji N, Walter J, Acker Y, Casarett D, Pollak K . The Use of Templates for Documenting Advance Care Planning Conversations: A Descriptive Analysis. J Pain Symptom Manage. 2023; 66(2):123-136. DOI: 10.1016/j.jpainsymman.2023.04.015. View

Caceres C, Heusser B, Garnham A, Moczko E . The Major Hypotheses of Alzheimer's Disease: Related Nanotechnology-Based Approaches for Its Diagnosis and Treatment. Cells. 2023; 12(23). PMC: 10705786. DOI: 10.3390/cells12232669. View

Akgonullu S, Yavuz H, Denizli A . SPR nanosensor based on molecularly imprinted polymer film with gold nanoparticles for sensitive detection of aflatoxin B1. Talanta. 2020; 219:121219. DOI: 10.1016/j.talanta.2020.121219. View

Tsung T, Tsai Y, Lee H, Chen Y, Lu D . Biodegradable Polymer-Based Drug-Delivery Systems for Ocular Diseases. Int J Mol Sci. 2023; 24(16). PMC: 10455181. DOI: 10.3390/ijms241612976. View

10.

Mitchell M, Billingsley M, Haley R, Wechsler M, Peppas N, Langer R . Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov. 2020; 20(2):101-124. PMC: 7717100. DOI: 10.1038/s41573-020-0090-8. View

11.

Rizvi S, Saleh A . Applications of nanoparticle systems in drug delivery technology. Saudi Pharm J. 2018; 26(1):64-70. PMC: 5783816. DOI: 10.1016/j.jsps.2017.10.012. View

12.

Ramachandran S, Satapathy S, Dutta T . Delivery Strategies for mRNA Vaccines. Pharmaceut Med. 2022; 36(1):11-20. PMC: 8801198. DOI: 10.1007/s40290-021-00417-5. View

13.

Hull S, Brunel L, Heilshorn S . 3D Bioprinting of Cell-Laden Hydrogels for Improved Biological Functionality. Adv Mater. 2021; 34(2):e2103691. PMC: 8988886. DOI: 10.1002/adma.202103691. View

14.

Wang Z, Tong Q, Li T, Qian Y . Nano drugs delivery system: A novel promise for the treatment of atrial fibrillation. Front Cardiovasc Med. 2022; 9:906350. PMC: 9645120. DOI: 10.3389/fcvm.2022.906350. View

15.

Santacruz-Marquez R, Gonzalez-De Los Santos M, Hernandez-Ochoa I . Ovarian toxicity of nanoparticles. Reprod Toxicol. 2021; 103:79-95. DOI: 10.1016/j.reprotox.2021.06.002. View

16.

Rabiee N, Ahmadi S, Fatahi Y, Rabiee M, Bagherzadeh M, Dinarvand R . Nanotechnology-assisted microfluidic systems: from bench to bedside. Nanomedicine (Lond). 2021; 16(3):237-258. DOI: 10.2217/nnm-2020-0353. View

17.

Enescu D, Cerqueira M, Fucinos P, Pastrana L . Recent advances and challenges on applications of nanotechnology in food packaging. A literature review. Food Chem Toxicol. 2019; 134:110814. DOI: 10.1016/j.fct.2019.110814. View

18.

Ezhilarasu H, Vishalli D, Dheen S, Bay B, Srinivasan D . Nanoparticle-Based Therapeutic Approach for Diabetic Wound Healing. Nanomaterials (Basel). 2020; 10(6). PMC: 7353122. DOI: 10.3390/nano10061234. View

19.

Kesharwani P, Tekade R, Jain N . Generation dependent cancer targeting potential of poly(propyleneimine) dendrimer. Biomaterials. 2014; 35(21):5539-48. DOI: 10.1016/j.biomaterials.2014.03.064. View

20.

Ramos T, Villacis-Aguirre C, Lopez-Aguilar K, Santiago Padilla L, Altamirano C, Toledo J . The Hitchhiker's Guide to Human Therapeutic Nanoparticle Development. Pharmaceutics. 2022; 14(2). PMC: 8879439. DOI: 10.3390/pharmaceutics14020247. View