Giant Cell Tumor of the Mandible: A Case Report with an Argument on a Possible Diagnostic Tool

Overview

Journal Indian J Otolaryngol Head Neck Surg

Publisher Springer

Date 2024 Aug 12

PMID 39130296

Authors

Ayushi Jain

Prashasti Chundawat

Shalini Gupta

Hari Ram

Affiliations

Soon will be listed here.

Abstract

Giant cell tumor (GCT) is a benign, locally aggressive neoplasm with a high recurrence rate with common occurrence in the long bone and the cases in the maxillofacial region bone are very rare. Due to the paucity of the cases, there is not enough information available regarding the behavior of the tumor. Also, the differentiation of this aggressive lesion with the commonly occurring reactive giant cell lesions is crucial and needs more research. This study is pertaining to the review of literature of the cases of GCT in the oral cavity with their clinicopathological, radiographic, and biochemical analyses. Although there are no available studies regarding the immunohistochemical characteristics of this lesion, this study is the first step in this direction to differentiate this tumor better and identify the possible pathogenesis.

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