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Effectiveness of Bone-filled Mesh Bag Technology and Angle Vertebroplasty in the Treatment of Osteoporotic Thoracic Vertebral Compression Fractures in the Elderly

Overview
Journal Am J Transl Res
Specialty General Medicine
Date 2024 Aug 8
PMID 39114704
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Abstract

Objective: To evaluate the effectiveness, pain level, and lung function in elderly patients with osteoporotic thoracic vertebral compression fractures using bone filling mesh bag technology compared to curved vertebroplasty.

Methods: This retrospective analysis reviewed 72 elderly patients with osteoporotic thoracic vertebral compression fractures treated at Xindu District People's Hospital of Chengdu between February 2021 and January 2022. The patients were separated into two groups according to surgery approach: an observation group using bone filling mesh bag technology and a control group using curved vertebroplasty. The overall response rate, pain degree, pulmonary function, life quality grades, surgical indicators, and bone cement leakage rates of the two groups were evaluated.

Results: The variation in overall response rate (P=0.420), pain degree (P=0.270), pulmonary function (peak expiratory flow: P=0.660, forced expiratory volume in the first second: P=0.775, forced vital capacity: 0.062), and life quality grades (physical health: P=0.949, social function: P=0.935, physiological function: P=0.970, vitality: P=0.778) between the observation group and the control group after treatment was not statistically meaningful. The Cobb angle (P<0.001) and vertebral height (P<0.001) of patients in the observation group were significantly higher than those in the control group after therapy. The leakage rates of bone cement (intervertebral disc leakage, paravertebral vein leakage, paravertebral soft tissue leakage) of patients in the observation group were notably lower than those in the control group after therapy (P=0.029).

Conclusion: Bone filling mesh bag technology offers significant improvements in Cobb angle and vertebral height for treating elderly patients with osteoporotic thoracic vertebral compression fractures, and reduced the leakage rate of bone cement. This technique achieves comparable therapeutic outcomes to curved vertebroplasty.

References
1.
Chen W, Tsai S, Goyal A, Fu T, Lin T, Bydon M . Comparison between vertebroplasty with high or low viscosity cement augmentation or kyphoplasty in cement leakage rate for patients with vertebral compression fracture: a systematic review and network meta-analysis. Eur Spine J. 2020; 30(9):2680-2690. DOI: 10.1007/s00586-020-06636-9. View

2.
Jin Y, Lee J, Xu B, Cho M . Effect of medications on prevention of secondary osteoporotic vertebral compression fracture, non-vertebral fracture, and discontinuation due to adverse events: a meta-analysis of randomized controlled trials. BMC Musculoskelet Disord. 2019; 20(1):399. PMC: 6717630. DOI: 10.1186/s12891-019-2769-8. View

3.
Su H, Ko H, Su Y, Lieu A, Lin C, Chang C . Prevention of Compression Fracture in Osteoporosis Patients under Minimally Invasive Trans-Foraminal Lumbar Interbody Fusion with Assistance of Bone-Mounted Robotic System in Two-Level Degenerative Lumbar Disease. Medicina (Kaunas). 2022; 58(5). PMC: 9147612. DOI: 10.3390/medicina58050688. View

4.
Mao W, Dong F, Huang G, He P, Chen H, Qin S . Risk factors for secondary fractures to percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a systematic review. J Orthop Surg Res. 2021; 16(1):644. PMC: 8556988. DOI: 10.1186/s13018-021-02722-w. View

5.
Kim J, Yoon D, Kim K, Shin D, Yi S, Kang J . Surgical Management of Gorham-Stout Disease in Cervical Compression Fracture with Cervicothoracic Fusion: Case Report and Review of Literature. World Neurosurg. 2019; 129:277-281. DOI: 10.1016/j.wneu.2019.05.235. View