Handgrip Strength and Clinical Evolution of People Living with HIV: A Mini Narrative Review

Overview

Journal Curr HIV Res

Publisher Bentham Science Publishers

Date 2024 Aug 8

PMID 39113304

Authors

Luiz Fernando Gouvea-E-Silva

Lorhoane Eduarda Simao de Morais

Giovana de Souza Goncalves

Morganna Alves Siqueira

Vitoria Souza Lima

Ludimila Paula Vaz Cardoso

Eduardo Vignoto Fernandes

Affiliations

Soon will be listed here.

Abstract

HIV infection is a worldwide epidemic. Antiretroviral therapy allows people living with HIV (PLHIV) increased longevity and a better quality of life. Among the various ways of monitoring the clinical evolution of PLHIV, handgrip strength (HGS) is a promising strategy, as this test can be used to assess the health condition quickly and at a low cost. In this sense, the present study aims to describe, through a literature review, the relationship between HGS and the clinical evolution of PLHIV, especially with morbimortality. Initially, it is highlighted that aging, HIV infection, and excess body fat are related to the loss of HGS in PLHIV. Furthermore, PLHIV is more likely to present cardiometabolic diseases that can be aggravated by reduced HGS. Thus, in people without positive HIV serology, low HGS indirectly, through the presence of risk factors or cardiometabolic diseases, or directly increases the chance of mortality. In conclusion, the lack of studies on this topic for PLHIV is highlighted, and more longitudinal studies, including control groups, are needed.

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