Titanium Tetrafluoride Catalysis for the Dehydrative Conversion of Diphenylmethanols to Symmetric and Unsymmetric Ethers

Overview

Journal RSC Adv

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2024 Aug 5

PMID 39101069

Authors

Aman G Singh

Abdulkhaliq A Alawaed

P Veeraraghavan Ramachandran

Affiliations

Soon will be listed here.

Abstract

In contrast to the conversion of diphenylmethanol to the corresponding halides with an equivalent of titanium tetrachloride or -bromide, catalytic (50 mol%) titanium tetrafluoride converts benzhydrols in diethyl ether or dichloromethane to bis(benzhydryl) ethers within 0.5-1 h at room temperature. Cross ether formation with diphenylmethanols and primary aryl or aliphatic alcohols is achieved in the presence of 25 mol% TiF in refluxing toluene as solvent. A tentative mechanism involving a carbocation intermediate has been proposed.

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