Biomarkers in Diagnosing and Therapeutic Monitoring of Tuberculosis: a Review

Overview

Journal Ann Med

Publisher Informa Healthcare

Specialty General Medicine

Date 2024 Aug 4

PMID 39097795

Authors

Sneha Leo

Meenakshi Narasimhan

Sridhar Rathinam

Antara Banerjee

Affiliations

Soon will be listed here.

Abstract

Tuberculosis (TB) continues to pose a significant health challenge worldwide, emphasizing the importance of prompt diagnosis and efficient monitoring of treatment outcomes for effective disease control. Biomarkers have become increasingly important in the realm of TB diagnoses and treatment. The objective of this comprehensive review is to examine the present state of biomarkers employed in the diagnosis of TB, monitoring the response to treatment, and predicting treatment outcomes. In this study, we undertake a comprehensive examination of the diverse biomarkers utilized in TB diagnoses, spanning molecular, immunological, and other novel methodologies. Furthermore, we examine the potential of biomarkers in the context of therapeutic monitoring, assessment of treatment effectiveness, and anticipation of drug resistance. Additionally, this paper presents future prospects regarding the utilization of biomarkers in the therapy of tuberculosis.

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