Diffuse Scalp Neurofibromas: Case Series and Clinicoradiological Characteristics of a Rare Vascular Lesion

Overview

Journal Interv Neuroradiol

Publisher Sage Publications

Specialty Neurology

Date 2024 Aug 2

PMID 39094573

Authors

Aaron Bleakley

Guy Betts

Sajid Sainuddin

Christopher Hilditch

Affiliations

Soon will be listed here.

Abstract

Diffuse neurofibroma of the head and neck are rare tumours which have unique clinical and radiological findings. Presurgical diagnosis is important as these lesions are usually highly vascular and pre-operative embolisation can reduce the risk of intra-operative haemorrhage. In this article we describe four cases; two which underwent pre-operative embolisation, which should aid the reader in successfully diagnosing this entity before biopsy/surgery.

References

Peh W, Shek T, Yip D . Magnetic resonance imaging of subcutaneous diffuse neurofibroma. Br J Radiol. 1998; 70(839):1180-3. DOI: 10.1259/bjr.70.839.9536912. View

Park S, Kim H, Ahn S . Piebaldism with neurofibromatosis type I: a familial case. Ann Dermatol. 2014; 26(2):264-6. PMC: 4037687. DOI: 10.5021/ad.2014.26.2.264. View

Kwon I, Cho Y, Lee S, Lee J, Cho K, Kim J . Poliosis circumscripta associated with neurofibroma. J Dermatol. 2005; 32(6):446-9. DOI: 10.1111/j.1346-8138.2005.tb00777.x. View

Huang G, Huang C, Lee H, Chang W, Lee C, Leu N . On the AJR viewbox. Diffuse neurofibroma of the arm: MR characteristics. AJR Am J Roentgenol. 2005; 184(5):1711-2. DOI: 10.2214/ajr.184.5.01841711. View

Tanaka J, Kuramochi A, Nishi N, Yuasa M, Heshiki A . Preoperative transarterial embolization enhances the surgical management of diffuse plexiform neurofibroma: a case report. Cardiovasc Intervent Radiol. 2005; 28(5):686-8. DOI: 10.1007/s00270-004-0230-2. View

Chiu Y, Dugan S, Basel D, Siegel D . Association of Piebaldism, multiple café-au-lait macules, and intertriginous freckling: clinical evidence of a common pathway between KIT and sprouty-related, ena/vasodilator-stimulated phosphoprotein homology-1 domain containing protein 1 (SPRED1). Pediatr Dermatol. 2012; 30(3):379-82. PMC: 3967413. DOI: 10.1111/j.1525-1470.2012.01858.x. View

Yoo K, Kim B, Rho Y, Lee J, Kim Y, Kim M . A case of diffuse neurofibroma of the scalp. Ann Dermatol. 2010; 21(1):46-8. PMC: 2883368. DOI: 10.5021/ad.2009.21.1.46. View

Ergun S, Emel E, Karabekir S, Buyukbabani N . Extracranial diffuse neurofibroma with intracranial extension. Plast Reconstr Surg. 2000; 105(2):801-3. DOI: 10.1097/00006534-200002000-00058. View

Needle M, Cnaan A, Dattilo J, CHATTEN J, Phillips P, Shochat S . Prognostic signs in the surgical management of plexiform neurofibroma: the Children's Hospital of Philadelphia experience, 1974-1994. J Pediatr. 1997; 131(5):678-82. DOI: 10.1016/s0022-3476(97)70092-1. View

10.

Ebrahim M, AlMutairi M, Hindi K, Bastaki J . Diffuse Neurofibroma in a Patient with Unknown History of NF1. Case Rep Otolaryngol. 2018; 2018:8768472. PMC: 6015682. DOI: 10.1155/2018/8768472. View

11.

Pereira V, Geiprasert S, Krings T, Caldas J, Toulgoat F, Ozanne A . Extracranial vertebral artery involvement in neurofibromatosis type I. Report of four cases and literature review. Interv Neuroradiol. 2010; 13(4):315-28. PMC: 3329237. DOI: 10.1177/159101990701300402. View

12.

Larson A, Brinjikji W, Anderson K, Tollefson M, Silvera V, Guerin J . Imaging of benign cervicofacial vascular anomalies and associated syndromes. Interv Neuroradiol. 2021; 28(3):364-374. PMC: 9185107. DOI: 10.1177/15910199211034989. View

13.

Hassell D, Bancroft L, Kransdorf M, Peterson J, Berquist T, Murphey M . Imaging appearance of diffuse neurofibroma. AJR Am J Roentgenol. 2008; 190(3):582-8. DOI: 10.2214/AJR.07.2589. View

14.

Sleiman R, Kurban M, Succaria F, Abbas O . Poliosis circumscripta: overview and underlying causes. J Am Acad Dermatol. 2013; 69(4):625-33. DOI: 10.1016/j.jaad.2013.05.022. View

15.

Sheerin U, Holmes P, Childs L, Roy A, Ferner R . Neurovascular complications in adults with Neurofibromatosis type 1: A national referral center experience. Am J Med Genet A. 2022; 188(10):3009-3015. DOI: 10.1002/ajmg.a.62931. View

16.

Kim S, Brinjikji W, Lanzino G, Kallmes D . Neurovascular manifestations of connective-tissue diseases: A review. Interv Neuroradiol. 2016; 22(6):624-637. PMC: 5564353. DOI: 10.1177/1591019916659262. View

17.

Deans W, Bloch S, Leibrock L, Berman B, Skultety F . Arteriovenous fistula in patients with neurofibromatosis. Radiology. 1982; 144(1):103-7. DOI: 10.1148/radiology.144.1.6806851. View

18.

Koplon B, Shapiro L . Poliosis overlying a neurofibroma. Arch Dermatol. 1968; 98(6):631-3. View

19.

Neri I, Liberati G, Piraccini B, Patrizi A . Poliosis and Neurofibromatosis Type 1: Two Familiar Cases and Review of the Literature. Skin Appendage Disord. 2017; 3(4):219-221. PMC: 5697512. DOI: 10.1159/000477445. View

20.

Jones R, Kiatisevi P, Morris D, Munk P, Clarkson P, Masri B . Intravascular embolisation and surgical resection of a giant neurofibroma with intratumoural haemorrhage. Br J Radiol. 2010; 83(995):e225-9. PMC: 3473718. DOI: 10.1259/bjr/42783229. View