Malignant Pleural Effusion: A Multidisciplinary Approach
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Malignant pleural effusion (MPE) has become an increasingly prevalent complication in oncological patients, negatively impacting their quality of life and casting a shadow over their prognosis. Owing to the pathophysiological mechanisms involved and the heterogeneous nature of the underlying disease, this entity is both a diagnostic and therapeutic challenge. Advances in the understanding of MPE have led to a shift in the treatment paradigm towards a more personalized approach. This article provides a comprehensive review and update on the pathophysiology of MPE and describes the diagnostic tools and the latest advances in the treatment of this complex clinical entity.
Krishnan S, Heisick J, Johnson M Cureus. 2025; 16(12):e76303.
PMID: 39850185 PMC: 11755966. DOI: 10.7759/cureus.76303.