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GDF11 (Protein of Juvenility) and GDF15 (Protein of Senility) in the Plasma of Patients with Sleep Apnea Syndrome: a Pilot Study

Overview
Journal Bull Exp Biol Med
Publisher Springer
Specialty General Medicine
Date 2024 Aug 1
PMID 39090465
Authors
I M Madaeva
E V Titova
O N Berdina
L F Sholokhov
N V Semenova
S I Kolesnikov
L I Kolesnikova
Affiliations
Soon will be listed here.
Abstract

We performed a matched-pair analysis of the content of GDF11 and GDF15 proteins in the plasma of patients (56 middle-aged men) with obstructive sleep apnea syndrome (OSAS) and healthy volunteers (27 men with no complaints of sleep disorders). The groups were comparable in terms of age and presence of chronic diseases. No statistically significant differences in GDF11 content in the studied groups were revealed, while the content of GDF15 in the OSAS group was 1.3 times higher. These results require further research from the viewpoint of geriatric somnology and molecular biology.

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