"Cruising Together"-ASC Specks and SAA, a Perfect Match in Chronic Inflammation
Overview
Overview
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Baroja-Mazo A, Martin-Sanchez F, Gomez A, Martinez C, Amores-Iniesta J, Compan V
. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat Immunol. 2014; 15(8):738-48.
DOI: 10.1038/ni.2919.
View
2.
Basiorka A, McGraw K, Abbas-Aghababazadeh F, McLemore A, Vincelette N, Ward G
. Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study. Lancet Haematol. 2018; 5(9):e393-e402.
PMC: 6505461.
DOI: 10.1016/S2352-3026(18)30109-1.
View
3.
Bertheloot D, Wanderley C, Schneider A, Schiffelers L, Wuerth J, Todtmann J
. Nanobodies dismantle post-pyroptotic ASC specks and counteract inflammation in vivo. EMBO Mol Med. 2022; 14(6):e15415.
PMC: 9174887.
DOI: 10.15252/emmm.202115415.
View
4.
Coll R, Schroder K, Pelegrin P
. NLRP3 and pyroptosis blockers for treating inflammatory diseases. Trends Pharmacol Sci. 2022; 43(8):653-668.
DOI: 10.1016/j.tips.2022.04.003.
View
5.
de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda C, Copeland C, Zhuang Y
. Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology. 2023; 78(1):225-242.
DOI: 10.1097/HEP.0000000000000298.
View