Case Report: F-FDG PET/CT Skeletal Superscan-like in an Adult Patient with Acute Lymphoblastic Leukemia

Overview

Journal Front Oncol

Specialty Oncology

Date 2024 Jul 30

PMID 39077465

Authors

Yu Hu

Wenli Dai

Peng Wang

Yawen Feng

Hui Feng

Jun Li

Affiliations

Soon will be listed here.

Abstract

We herein describe a rare case of adult acute lymphoblastic leukemia with an florine-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) skeletal superscan-like appearance. The degree of bone marrow uptake was so intense that it far exceeded the level of physiological cerebral uptake and radiourinary activity. The distribution was remarkably similar to a superscan seen on skeletal scintigraphy. Skeletal superscans of F-FDG PET/CT have been reported in hematological diseases, solid tumors with extensive bone metastasis, and metabolic diseases. Thus, we reviewed the PET/CT images of cases reported, indicating that more homogeneous distribution, without primary tumor and specific mandibular and skull activity, may be suggestive of hematological diseases.

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