Streptococcus Taoyuanensis Sp. Nov., a Novel Species Isolated from a Patient with Bacteremia

Overview

Journal Curr Microbiol

Specialty Microbiology

Date 2024 Jul 29

PMID 39073451

Authors

Chien-Yu Lee

Chin-Kan Chan

Yi-Sheng Chen

Yun-Shien Lee

Shih-Ting Lin

Yu-Chung Chang

Hui-Chung Wu

Jia-Rong Zhang

Hong-Yu Chen

Li-Ting Wang

Affiliations

Soon will be listed here.

Abstract

Streptococcus spp. are important opportunistic pathogen of bacteremia in both immunocompetent and immunosuppressed patients. A streptococcal strain, designated ST2, was isolated from the blood specimen of a bacteremic patient. Comparative analyses of 16S rRNA, rpoB and groEL gene sequences demonstrated that the novel strain ST2 is a member of the genus Streptococcus. Based on of 16S rRNA gene sequence similarities, the type strains of Streptococcus (S.) parasanguinis (99.2%), S. ilei (98.8%), S. oralis subsp. oralis (97.6%), S. australis (97.5%) and S. sanguinis (97.5%) were the closest neighbours to strain ST2. The housekeeping gene sequences (rpoB and groEL) similarities of strain ST2 to these closely related type strains were 80.4-97.4%, respectively. The complete draft genome of strain ST2 consisted of 2,155,906 bp with a G + C content of 42.0%. Strain ST2 has an average nucleotide identity (ANI) value of 94.1 and 81.3% with S. parasanguinis ATCC 15912 and S. ilei I-G2, respectively. The highest in silico DNA-DNA hybridization value with respect to the closest species S. parasanguinis was 55.6%, below the species cut-off of 70% hybridization. The primary cellular fatty acids of strain ST2 were C, C ω9c, C and C. Based on biochemical criteria and molecular genetic evidence, it is proposed that strain ST2 be assigned to a new species of the genus Streptococcus as Streptococcus taoyuanensis sp. nov. The type strain of Streptococcus taoyuanensis is ST2 (=NBRC 115928 = BCRC 81374) as the type strain.

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